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This Cannabis Study Shows Promising Results for Bone Regeneration

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By Chane Leigh
Source: medicalcannabisbrief.com

This Cannabis Study Shows Promising Results for Bone Regeneration

Did you know that during childhood and your teen years, your body is busy adding on new bone much faster than it can remove the old bone? However, now that you’re an adult, you’re losing bone faster than you can make it. For some people, their bones can be riddled with problems, and since we need our bones for movement and support, taking care of them and getting effective treatment when necessary is imperative. Fortunately,  a recent study revealed that cannabinoids can be effective in the regeneration of bone. 

Bone Diseases 

Even if one makes sure to get enough calcium, vitamin D and exercise to maintain bone health, they can still suffer from bone disease. Many bone diseases leave the bones weak and easy to break. Individuals suffering from bone problems may encounter low bone density, osteoporosis (porous bone), osteogenesis imperfecta (formation of bone is imperfect), cancer, infections as well as problems with bone regrowth or rebuilding. 
The average human has 206 bones in their bodies, bones which are also living tissue and that living tissue continuously goes through cycles of renewal. The condition of our bones is often measured by screening for its density or mass, which can serve as an indicator of how strong, or weak, the bones are. 

10 Of the Most Common Bone Disorders:

  • Osteoporosis is the most common and involves having bones of low density, meaning they are weak and brittle. 
  • Paget’s Disease is a bone disorder where the bone renewal cycle happens too quickly, which then leads to deformities or/and enlarged bones. 
  • Bone Infection is often referred to as osteomyelitis which is rare but serious. This disease is often contracted after major surgery and can spread through the whole body. 
  • Osteonecrosis is when bone tissue dies off because it has restricted or disrupted blood flow to the area. 
  • Bone Tumors happen when cells grow uncontrollably from the inside of the bone. These can be benign (non-cancerous) or malignant (cancerous). 
  • Osteoarthritis is a chronic disease which is characterized by the chronic degeneration of the joints. 
  • Rheumatoid Arthritis is a disease where the body mistakenly attacks parts of the body such as the joints or bones in hands and feet. 
  • Scoliosis is the condition of having a spine that curves abnormally to the right or left. 
  • Low Bone Density, which is sometimes referred to as osteopenia, can lead to osteoporosis (number 1). This condition just means that the density is lower than it should be but that steps can be taken to improve it before a more serious condition occurs. 
  • Gout is a disorder when the joints, particularly the big toe, are inflamed due to excess uric acid crystal build-up in the joints. 
All of these diseases leave the individual with pain, redness, swelling, and inflammation of the bone.
Irrespective of what bone disease an individual may be struggling with, cannabis can help to reduce the pain, inflammation, and even promote the regeneration of bone. Since most of the conditions leave the bones weaker, making use of medical benefits from cannabis can improve the condition, alleviate side effects, and promote the strengthening of bone by regeneration (or regrowth).   

The Bone Regeneration Study

Simply explained, the ECS can signal for osteoblast (creation of new bone) formation, bone formation as well as osteoclast (absorb and remodel bone) activity. When cannabis is consumed, the ECS is stimulated by cannabis, it effectively boosts osteoblast and osteoclast activity. 
The researchers of the study stated that “an optimal correlation of dose, duration, moment of action, and affinity can lead to an increased bone regeneration capacity, with important benefits in many pathological situations which involve bone tissue”.
  • Bone cells express cannabinoid receptors and secrete endocannabinoid metabolizing enzymes. 
  • Cannabinoids have an important role in the regulation of bone remodeling and mass. 
  • Tetrahydrocannabinol (THC) is known to target the CB-1 and CB-2 receptors in the ECS, yet their results displayed that cannabidiol (CBD) enhanced the healing of fractures more. 
  • However, the same study found that the CBD acts as a moderator of the effects of THC and thus, in the cause of osteoblasts and faster bone healing, supporting the study on bone regeneration. The combination of THC and CBD needs to be an optimal correlation of the aspects mentioned above. 
Dragos and his team go on to suggest that since the “adverse reactions of cannabinoids have not been described in patients under controlled medication, cannabinoids can represent future treatment for bone regeneration”. 
Remember that prevention is better than experiencing the problem. Take your vitamins, take your bones for a walk or some exercise, avoid drinking too much alcohol and smoking as well as remembering that cannabis is regarded as one of the safest and most beneficial substances on the planet and can be used for an array of conditions and reasons. Do not delay on benefiting from cannabis, especially when your condition could improve from it. 

Source: http://hemplogic.blogspot.com/2020/08/this-cannabis-study-shows-promising.html

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Newbie q: Is Broad Spectrum worth taking over Isolate?

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Does the extra substances in Broad spectrum really have any benefit without any THC?

I read the following but I dont know enough yet to agree or not: “You cannot get an entourage effect without THC. You cannot therefore completely extract the THC and call it anything but an isolate. You most certainly cannot claim it gives “the benefits of a full spectrum” because it literally cannot do so. There is no such thing as “broad spectrum.” It’s a nonsense term that companies selling isolates are using to trick you into buying their weakened products.”

What are the thoughts of people, esp. those who’ve tried broad and isolate?

Source: https://www.reddit.com/r/CBD/comments/jkz9ic/newbie_q_is_broad_spectrum_worth_taking_over/

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HOPE™ Products for Autism Launch in Australia After Earlier US Debuts in Pennsylvania and Louisiana

Zelira Therapeutics Ltd (ASX: ZLD, OTCQB: ZLDAF) just announced that its proprietary cannabinoid medicines, HOPE 1™ and HOPE 2™are now available by prescription to patients in Australia. The HOPE™ forumations, developed by Zelira and noted autism advocate Erica Daniels, first launched in 2019 in Pennsylvania and this fall in Louisiana.  “We have had great success […]

The post HOPE™ Products for Autism Launch in Australia After Earlier US Debuts in Pennsylvania and Louisiana appeared first on Green Market Report.

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Zelira Therapeutics Ltd (ASX: ZLD, OTCQB: ZLDAF) just announced that its proprietary cannabinoid medicines, HOPE 1 and HOPE 2are now available by prescription to patients in Australia. The HOPE™ forumations, developed by Zelira and noted autism advocate Erica Daniels, first launched in 2019 in Pennsylvania and this fall in Louisiana. 

“We have had great success with HOPE™ in the US and are thrilled to be able to offer it to patients as a treatment option through the Therapeutic Goods Administration’s (TGA) Special Access Scheme,” says Osagie Imosogie, Chairman of Zelira Therapuetics. “Zelira is proud of this latest achievement in our mission to bring cannabinoid medicine to patients around the world.”

The HOPE cannabinoid medicines were developed to support the needs of patients with Autism Spectrum Disorder (ASD) by Daniels and Zelira Therapeutics, which then licensed the proprietary formulas to Ilera Healthcare in Pennsylvania and Ilera Holistic Healthcare in Louisiana. HOPE has since established itself as one of the top selling formulated medicinal cannabis products in Ilera Healthcare’s portfolio. 

“Autism families are finally beginning to have access to a truly better alternative than the harsh pharmaceuticals of the past and I am so proud that HOPE is now available in Australia,” says Erica Daniels, founder of Hope Grows for Autism and co-creator of the HOPE forumalations. “What started off as a labor of love to find a way to treat my own son is now helping parents around the world.” 

HOPE is part of Zelira’s family of revenue generating medicinal cannabis formulations. The products consist of two pharmaceutical-grade proprietary formulations developed as pharmaceutical-grade products targeting Autism Spectrum Disorder (ASD) as a disease indication. 

“Following the success of the HOPE™ launches in Pennsylvania and Louisiana, we are excited to make these products available to patients and physicians in Australia,” says Dr. Richard Hopkins, Zelira’s global Managing Director. “This represents another key milestone in our commitment to bring the benefits of HOPE to patients in global markets.”


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Source: https://www.greenmarketreport.com/hope-products-for-autism-launch-in-australia-after-earlier-us-debuts-in-pennsylvania-and-louisiana/?utm_source=rss&utm_medium=rss&utm_campaign=hope-products-for-autism-launch-in-australia-after-earlier-us-debuts-in-pennsylvania-and-louisiana

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How long till I have a “normal” THC high again after vaping CBD?

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This week I started vaping CBD to try and cut back on my weed consumption during the week as it was starting to interfere with my college classes. The results have blown me out of the water so far, but I’ve also noticed how dampened my THC highs have become. I’m fine with it during the week as I don’t feel awful waking up after a late night sesh and can get my stuff done, but over the weekend I like to indulge a little more since I’ve cut back so much during the week. About how long does it typically take after pausing CBD consumption (I last vaped around 6 pm yesterday) to feel a full, normal high? I do appreciate the calm nature of the highs when you’re loaded up with CBD but it’s just not as satisfying for me in my free time. Any help appreciated 🙂

Source: https://www.reddit.com/r/CBD/comments/jky9co/how_long_till_i_have_a_normal_thc_high_again/

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