This year, for the first time, the number of entities cultivating cannabis with the approval of the US federal government will be more than one.
For decades, cannabis has been cultivated at the University of Mississippi and shipped to researchers across the country. Last month, the US Drug Enforcement Administration finalized regulations to allow for additional licenses, as Cannabis Wire reported, four years after the agency first announced it would do so. Those regulations take effect on January 19, after which the DEA will begin to issue licenses to entities that have applied.
The DEA has not yet indicated just how many licences it will issue, but, as Cannabis Wire has reported, several major companies want in. When the DEA first announced its plans, more than thirty applications came in, including from cannabis giant Canopy Growth to existing government-contractor Battelle. (It is not clear whether any of the companies that applied years ago have decided not to move forward.)
Now, Cannabis Wire has identified an additional thirteen applications that have rolled in after the DEA published the initial list in August 2019.
Here are the newer applicants:
SAMHSA: Newly Popular Cannabis Compounds Are Complicating Impairment Testing
The rising popularity of cannabis and, more recently, some of its compounds, like cannabidiol (CBD) and Delta-8-THC, has complicated the research community’s understanding of impairment. That was a repeated theme on Tuesday, during the latest Substance Abuse and Mental Health Services Administration (SAMHSA) Drug Testing Advisory Board (DTAB) meeting. A decade ago, cannabis, which contains […]
The rising popularity of cannabis and, more recently, some of its compounds, like cannabidiol (CBD) and Delta-8-THC, has complicated the research community’s understanding of impairment.
That was a repeated theme on Tuesday, during the latest Substance Abuse and Mental Health Services Administration (SAMHSA) Drug Testing Advisory Board (DTAB) meeting. A decade ago, cannabis, which contains dozens of compounds known as cannabinoids, was most often associated with its dominant cannabinoid, delta-9-tetrahydrocannabinol (THC). Even today, while cannabis is legal for adult use in 15 states and Washington, D.C., research is inconclusive when it comes to how, or how much, THC leads to impairment, on the road and elsewhere, and there is no national consensus as there is for alcohol (.08% BAC). And now, researchers are scrambling to account for differences depending on whether the consumed cannabis products also contained CBD, and whether they were consumed via, say, vape or edible.
During his introductory remarks about the “evolving environment,” Ron Flegel, the chair of the Board, said that the passage of the 2018 Farm Bill, which legalized cannabis with .3% THC or less, also known as hemp, “had an effect on the drug testing industry.”
Flegel noted the “increased public acceptability, and definitely availability, of marijuana and CBD products, and the implications for workplace safety and security,” and flagged “as an emerging issue, the Delta-8-THC or other THC isomers.” Flegel added that “the Delta-8 is an impairing substance, and it is being marketed on the Internet dramatically as we speak.”
In short, when the federal government singled out delta-9-tetrahydrocannabinol in defining hemp as the legal form of cannabis, everything else that comes from the cannabis plant, such as CBD or Delta-8, became fair game. Hemp-derived CBD, which does not cause a high, has been on mainstream shelves for years, while Delta-8, which does cause a high, is a much more recent trend, and, as Flegel noted, is so far found most often through online retailers.
SAMHSA’s Division of Workplace Programs, which oversees the Federal Drug-free Workplace Program, has been working with researchers from Johns Hopkins University for nearly a decade to try to better understand cannabis impairment, and invited them to present their most recent findings during Tuesday’s meeting.
Researcher Ryan Vandrey began by providing an overview of the legal landscape of cannabis today, where medical cannabis is available in dozens of states and cannabis is legal for adult use in 15 states and D.C.
“The result of that legalization is that joints and blunts are no longer all we think about when it comes to cannabis,” Vandrey said. “The term ‘cannabis’ now has become an umbrella that covers hundreds of different distinct products. And these products are distinct both in the route of administration in which they’re administered. It varies in the formulation, it varies in the chemical composition. And so the complexities abound in terms of how we understand and how we think about cannabis and cannabinoid products.”
So far, the researchers have found in several published studies, for example, that secondhand exposure to smoked cannabis joints with 12% THC in an unventilated room can lead to detectable THC in blood, and, looking at urine, Vandrey said that they “had a single specimen that was a true positive in accordance with current federal drug testing methodologies.”
They also found that 10 mg of THC vaped is felt more strongly than if smoked. That is reflected in the consumer’s heart rate, which increases more with a vaped product, and in their psychomotor skills, which are more negatively affected.
When it comes to CBD, the team looked at 100 mg CBD (vaped and orally ingested), at 100 mg CBD with the addition of 3.7 mg THC (vaporized), and at a placebo. They found that women more often than men reported a “pleasant drug effect.” Also, they found no “cardiovascular outcomes” with the pure CBD products. And, Vandrey added, they “noted no impact of any dose or formulation in this study on cognitive performance outcomes.”
Forthcoming research from the Johns Hopkins team will examine topical cannabis products and Delta-8-THC dosing.
Prior to the presentation of cannabis studies, Capt. Eric Welsh, the Director of the Office of Drug Demand Reduction in the Department of Defense provided an update on drug testing of Department of Defense service members. In FY 2019, he said, cannabis accounted for 77.8% of all positive tests of service members. Though, overall, cannabis-positive tests are lower today than they were a decade ago, before any state legalized cannabis for adult use.
“People ask constantly if we’re seeing an impact of legalization, decriminalization efforts,” he said. “We actually saw a pretty significant decrease from 2009 to 2014, and now we’re starting to slowly see that climb back up. Whether that’s from decriminalization or not, it’s hard to tell, but it’s something we continue to monitor.”
The DTAB meeting continued into the afternoon, but was closed to the public and the press. On the agenda was an “FDA CBD Presentation,” which included “FDA Staff,” FDA’s Cannabidiol (CBD) Policy Working Group,” and “FDA/Office of the Commissioner (OC)/Office of Clinical Policy & Programs (OCPP).”
After the passage of the 2018 Farm Bill, the Food and Drug Administration was tasked with crafting rules for hemp-derived products containing cannabinoids, including everything from foods and beverages to supplements and cosmetics. That process is ongoing.
Ayahuasca In the Fight Against Drug Addiction
Drug addiction is a major issue in the modern world with sky-high numbers for deaths due to drugs throughout the world each year. Very little in the standard medical world has provided an answer to the question of how to break a drug addiction, and recidivism rates for addicts have always remained high. New research […]
Drug addiction is a major issue in the modern world with sky-high numbers for deaths due to drugs throughout the world each year. Very little in the standard medical world has provided an answer to the question of how to break a drug addiction, and recidivism rates for addicts have always remained high. New research into the medical properties of ayahuasca indicates it might be an answer in the fight against drug addiction.
Psychedelics are becoming popular once again, and THC, which is often considered a psychedelic, is one of the most in-demand. These days there are options when it comes to THC. You can go with standard delta-9, or opt for less psychoactive effect and less anxiety with delta-8 THC. Want to give it a shot? Check out these great Delta-8 THC deals, and try the ‘other’ THC.
The US drug overdose issue
Some people will attribute any use of drugs to there being a drug problem. Consider that for decades, marijuana smoking was treated the same as heroin use, though today it’s clear that it doesn’t deserve that treatment. Trying to determine who has a drug issue is moot in the end, as it almost doesn’t matter. One of the ways to judge a drug issue is by the problems that come out if it, with the biggest ones being drug-related violence and deaths. So rather than worry about how many people are using drugs in a way that might be defined as problematic, let’s instead look at drug deaths to gauge the issue.
There are plenty of different national and international reporting agencies about drugs, often with different numbers coming out, though they tend to be in the same direction. It’s also hard to get full global statistics, so sometimes the best possible option is to investigate particular locations to see trends.
According to the CDC, the first three months of 2020 saw approximately 19,416 drug overdose deaths in the US alone. The same period from one year earlier had about 16,682, nearly three thousand less. In the CDC’s US Centers for Disease Control and Prevention’s National Center for Health Statistics report from October of 2020, the agency also approximated 75,500 overdose deaths between March 2019 and March 2020.
CBD News Roundup: Study Reveals 90% Genetic Overlap Between High-CBD Hemp and High-THC Marijuana
Here’s the latest CBD news: A University of Minnesota study demonstrates the strong genetic similarities between high-CBD cannabis and marijuana. The Indiana state legislature is in the process of reversing their smokable hemp ban as established in 2019 regulations. Table of Contents Study Reveals 90% Genetic Overlap Between High-CBD Hemp and High-THC Marijuana Indiana State… View Article
The post CBD News Roundup: Study Reveals 90% Genetic Overlap Between High-CBD Hemp and High-THC Marijuana appeared first on The CBD Insider.
Here’s the latest CBD news:
- A University of Minnesota study demonstrates the strong genetic similarities between high-CBD cannabis and marijuana.
- The Indiana state legislature is in the process of reversing their smokable hemp ban as established in 2019 regulations.
Table of Contents
- Study Reveals 90% Genetic Overlap Between High-CBD Hemp and High-THC Marijuana
- Indiana State House Votes to Lift Smokable Hemp Ban
Study Reveals 90% Genetic Overlap Between High-CBD Hemp and High-THC Marijuana
University of Minnesota researchers investigating the genetic ancestry of high-CBD cannabis strains discovered that the overwhelming majority of genes inherited by these plants come from high-THC marijuana.
The authors used DNA sequencing to map out the CBD genome, specifically measuring for “cannabinoid synthase” enzymes, which are responsible for the production of cannabinoids (THC, CBD, etc.).
They found that, while the CBD strain they were assessing inherited most of its genes from older marijuana strains, two key differences allow for its low-THC and high-CBD content:
- Hybridization of ancestral marijuana with hemp encouraged “cannabidiolic acid synthase” (pro-CBD enzyme) in the tested plants.
- The tested plants lacked a “complete sequence for tetrahydrocannabinolic acid synthase (THAS).”
From a consumer standpoint, there’s no reason to abandon CBD for fear of THC content.
After all, pigs are almost genetically identical to humans, but the mysterious ways in which our snippets of genetic code communicate and work with each other allows for consistent, distinct differences.
Indiana State House Votes to Lift Smokable Hemp Ban
A bill passed by the Indiana House this month (69-28 votes) seeks to roll back a number of provisions designed to restrict the production and sale of smokable hemp flower in the state as outlined in 2019 regulatory legislation.
A federal-level challenge to the ban resulted in House Bill No. 1224, which had to amend, repeal, and otherwise modify upwards of a dozen existing laws to legitimize the production and sale of smokable hemp flower.
These changes include, but are not limited to the following:
- The state seed commissioner may not adopt or enforce a rule that is more strict than required under federal law or regulation.
- Repeals a law that requires that a hemp bud or flower be sold only to a processor licensed in Indiana.
- Provides that a food is not considered adulterated for containing low-THC hemp extract or craft hemp flower.
- Creates contaminant testing and packaging requirements for the distribution and sale of craft hemp flower.
- “Craft hemp flower” is not included in the definition of “controlled substance analog,” “hashish,” “low-THC hemp extract,” or “marijuana.”
- Repeals the definition of “smokable hemp” and criminal penalties concerning smokable hemp.
In other words, Indiana House Bill No. 1224 would pave the way for the legal manufacturing, distribution, and public consumption of hemp flower.
The majority of state legislatures have not yet made their stance on the matter, but twelve have either enacted a ban, rejected a ban, or are currently deliberating over the matter.
If the Indiana senate passes House Bill No. 1224, they will become the second state (North Carolina is the first) to reject a smokable hemp ban.
Hello, im new to CBD and I just got this e-liquid and a pen. I looked up the vape juice after, and it doesn’t seem to exist.. Has anyone else used this brand?
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