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The Benefits of CBD Cream for Rosacea

Rosacea is a common skin condition, and if you have it, you don’t need to be told how difficult it can be to find a skin care product that’s effective, safe, and easy to use. While not curable per se, rosacea may come and go. Keep in mind, however, that just because your rosacea has disappeared doesn’t mean it won’t return. In fact, it almost certainly will. That’s why regular use of rosacea remedies can keep this skin condition at bay.
CBD has been demonstrated to have the ability to significantly reduce the symptoms of rosacea. Thanks in part to its gentleness and potency as an anti-inflammatory. It’s not just about anecdotal evidence, either. Recent studies show that CBD skin care does have major benefits for the skin — especially for people with inflammatory skin conditions like rosacea.

Published

11 months ago

February 14, 2020

Republished by Plato

Rosacea is a common skin condition, and if you have it, you don’t need to be told how difficult it can be to find a skin care product that’s effective, safe, and easy to use. While not curable per se, rosacea may come and go. Keep in mind, however, that just because your rosacea has disappeared doesn’t mean it won’t return. In fact, it almost certainly will. That’s why regular use of rosacea remedies can keep this skin condition at bay.
CBD has been demonstrated to have the ability to significantly reduce the symptoms of rosacea. Thanks in part to its gentleness and potency as anti-inflammatory. It’s not just about anecdotal evidence, either. Recent studies show that CBD skin care does have major benefits for the skin — especially for people with inflammatory skin conditions like rosacea.

The list of CBD’s health benefits is long, but there are some that are more specifically relevant to skin conditions like rosacea than others. Below, you’ll find two of the most compelling reasons researchers believe CBD can reduce the symptoms of rosacea and restore balance to the skin.

CBD Is Anti-Inflammatory
Like all inflammatory skin conditions, rosacea is the product of a normal immune response whereby the immune system thinks that an area of skin or tissue is under attack, and causes it to swell up for protection while white blood cells work on the healing process. But when the inflammatory response is overactive, as it is in rosacea, it can cause redness, pain, and irritation.

Research has shown that CBD is a powerful anti-inflammatory. Not only is it able to reduce inflammation, but it also causes fewer side effects than conventional anti-inflammatory drugs. Those can often lead to stomach pain, ulcers, headaches, and dizziness. CBD, on the other hand, hasn’t been shown to cause any severe side effects despite working just as well at reducing inflammation.

CBD Relieves Pain
Rosacea varies widely in its severity, but people who suffer from the most pronounced forms of the condition often complain that the affected skin can be very tender to the touch and even painful. The skin can form bumps of various sizes that become sore, and its surface can experience a relentless burning sensation. In some cases it can affect the eyes, too, causing irritation and stinging.

CBD creams can relieve this discomfort by working with the endocannabinoid system, which is one of the body’s systems that helps regulate the perception of pain. As a bonus, they don’t cause the side effects associated with other topical pain treatments like steroid creams, which can thin the skin if used too often. CBD creams are gentle enough to be used on even the most sensitive skin.

The gentle but effective pain-relieving and anti-inflammatory properties of CBD oil make it an ideal treatment for rosacea-prone skin. It won’t cure the condition, but a high quality CBD cream could make living with it much easier, which should come as welcome news to anyone trying to find a treatment that works for them.

Source: https://www.bestfeeling.co.uk/blogs/news/the-benefits-of-cbd-cream-for-rosacea

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The Role of Cannabinoids as Anticancer Agents in Pediatric Oncology

Published

2 hours ago

January 20, 2021

Republished by Plato

Cannabinoids are a group of chemicals that bind to receptors in the human body and, in turn, modulate the endocannabinoid system (ECS). They can be endogenously produced, synthetic, or derived from the plant Cannabis sativa L. Research over the past several decades has shown that the ECS is a cellular communication network essential to maintain multiple biological functions and the homeostasis of the body. Indeed, cannabinoids have been shown to influence a wide variety of biological effects, including memory, pain, reproduction, bone remodeling or immunity, to name a few. Unsurprisingly, given these broad physiological effects, alterations of the ECS have been found in different diseases, including cancer. In recent years, the medical use of cannabis has been approved in different countries for a variety of human conditions. However, the use of these compounds, specifically as anticancer agents, remains controversial. Studies have shown that cannabinoids do have anticancer activity in different tumor types such as breast cancer, melanoma, lymphoma and adult brain cancer. Specifically, phytocannabinoids Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) has been shown to induce apoptosis and inhibit proliferation of adult cancer cells, as well as modulate angiogenesis and metastasis. Despite increasing evidence that cannabinoids elicit antitumor effects in adult cancers, there is minimal data available on their effects in children or in pediatric cancers despite public and clinical demand for information. Here we describe a comprehensive and critical review of what is known about the effects of cannabinoids on pediatric cancers, highlight current gaps in knowledge and identify the critical issues that need addressing before considering these promising but controversial drugs for use in pediatric oncology.

Keywords: CBD; THC; cannabidiol; cannabinoid; childhood cancer; medical cannabis; pediatric oncology; Δ9-tetrahydrocannabinol.

Source: https://pubmed.ncbi.nlm.nih.gov/33466435/?utm_source=no_user_agent&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zmroqAMnEquTZFTfdGx1V1gPEavo-Be3-FKTecJpOlB7LykCL&fc=20200804213506&ff=20210120135252&v=2.14.2

Heartland

Cannabis sativa L. as a Natural Drug Meeting the Criteria of a Multitarget Approach to Treatment

Cannabis sativa L. turned out to be a valuable source of chemical compounds of various structures, showing pharmacological activity. The most important groups of compounds include phytocannabinoids and terpenes. The pharmacological activity of Cannabis (in epilepsy, sclerosis multiplex (SM), vomiting and nausea, pain, appetite loss, inflammatory bowel diseases (IBDs), Parkinson’s disease, Tourette’s syndrome, schizophrenia, glaucoma, and coronavirus disease 2019 (COVID-19)), which has been…

Published

2 hours ago

January 20, 2021

Republished by Plato

Cannabis sativa L. turned out to be a valuable source of chemical compounds of various structures, showing pharmacological activity. The most important groups of compounds include phytocannabinoids and terpenes. The pharmacological activity of Cannabis (in epilepsy, sclerosis multiplex (SM), vomiting and nausea, pain, appetite loss, inflammatory bowel diseases (IBDs), Parkinson’s disease, Tourette’s syndrome, schizophrenia, glaucoma, and coronavirus disease 2019 (COVID-19)), which has been proven so far, results from the affinity of these compounds predominantly for the receptors of the endocannabinoid system (the cannabinoid receptor type 1 (CB₁), type two (CB₂), and the G protein-coupled receptor 55 (GPR₅₅)) but, also, for peroxisome proliferator-activated receptor (PPAR), glycine receptors, serotonin receptors (5-HT), transient receptor potential channels (TRP), and GPR, opioid receptors. The synergism of action of phytochemicals present in Cannabis sp. raw material is also expressed in their increased bioavailability and penetration through the blood-brain barrier. This review provides an overview of phytochemistry and pharmacology of compounds present in Cannabis extracts in the context of the current knowledge about their synergistic actions and the implications of clinical use in the treatment of selected diseases.

Keywords: Cannabis; multitarget; phytocannabinoids (THC and CBD); receptors; terpenes.

Source: https://pubmed.ncbi.nlm.nih.gov/33466734/?utm_source=no_user_agent&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zmroqAMnEquTZFTfdGx1V1gPEavo-Be3-FKTecJpOlB7LykCL&fc=20200804213506&ff=20210120135252&v=2.14.2

Heartland

Pervasive cropland in protected areas highlight trade-offs between conservation and food security

Published

2 hours ago

January 20, 2021

Republished by Plato

. 2021 Jan 26;118(4):e2010121118.

doi: 10.1073/pnas.2010121118.

Affiliations

Item in Clipboard

Varsha Vijay et al. Proc Natl Acad Sci U S A. 2021.

. 2021 Jan 26;118(4):e2010121118.

doi: 10.1073/pnas.2010121118.

Affiliations

¹ National Socio-Environmental Synthesis Center, University of Maryland, Annapolis, MD 21401; vvijay@sesync.org.
² Department of Ecology and Evolutionary Biology and National Institute for Mathematical and Biological Synthesis, University of Tennessee, Knoxville, TN 37996.

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Abstract

Global cropland expansion over the last century caused widespread habitat loss and degradation. Establishment of protected areas aims to counteract the loss of habitats and to slow species extinctions. However, many protected areas also include high levels of habitat disturbance and conversion for uses such as cropland. Understanding where and why this occurs may realign conservation priorities and inform protected area policy in light of competing priorities such as food security. Here, we use our global synthesis cropland dataset to quantify cropland in protected areas globally and assess their relationship to conservation aims and socio-environmental context. We estimate that cropland occupies 1.4 million km² or 6% of global protected area. Cropland occurs across all protected area management types, with 22% occurring in strictly protected areas. Cropland inside protected areas is more prevalent in countries with higher population density, lower income inequality, and with higher agricultural suitability of protected lands. While this phenomenon is dominant in midnorthern latitudes, areas of cropland in protected areas of the tropics and subtropics may present greater trade-offs due to higher levels of both biodiversity and food insecurity. Although area-based targets are prominent in biodiversity goal-setting, our results show that they can mask persistent anthropogenic land uses detrimental to native ecosystem conservation. To ensure the long-term efficacy of protected areas, post-2020 goal setting must link aims for biodiversity and human health and improve monitoring of conservation outcomes in cropland-impacted protected areas.

Keywords: CBD; area-based targets; conservation; food security; protected areas.

Conflict of interest statement

The authors declare no competing interest.

References

1. Klein Goldewijk K., Beusen A., Doelman J., Stehfest E.. New anthropogenic land use estimates for the holocene: HYDE 3.2. Earth Syst. Sci. Data. 2017;9:927–953.
1. Barrett C. B.. Measuring food insecurity. Science. 2010;327:825–828.
1. Fogel R. W.. The Escape from Hunger and Premature Death, 1700-2100: Europe, America, and the Third World. 2004.
1. Crist E., Mora C., Engelman R.. The interaction of human population, food production, and biodiversity protection. Science. 2017;356:260–264.
1. Pimm S. L., Vijay V.. Population, Agriculture, and Biodiversity: Problems and Prospects. 2020;365.