Connect with us

Heartland

Neuropsychiatric Sequelae in Adolescents With Acute Synthetic Cannabinoid Toxicity

CONCLUSIONS: In this multisite cohort of US adolescents assessed in the ED, SC exposure was associated with higher odds of neuropsychiatric morbidity than cannabis exposure providing a distinct neurospychiatric profile of acute SC toxicity in adolescents.

Republished by Plato

Published

on

Background and objectives: Adolescents represent the largest age group that presents to emergency departments (ED) for synthetic cannabinoid (SC) toxicity; however, the neurotoxic effects of acute SC exposures in this group are understudied. Our aim was to characterize the neuropsychiatric presentation of adolescents with SC-related exposure in the ED compared with those with traditional cannabis exposure.

Methods: A multicenter registry of clinical information prospectively collected by medical toxicologists (Toxicology Investigators Consortium Case Registry) was reviewed for adolescents presenting to the ED after SC or cannabis exposure from 2010 through 2018. Associations were measured between drug exposures and neuropsychiatric symptoms and/or signs. Exposures were classified into 4 groups: SC-only exposure, SC-polydrug exposures, cannabis-only exposure, and cannabis-polydrug exposures.

Results: Adolescents presenting to the ED with SC-only exposure (n = 107) had higher odds of coma and/or central nervous system depression (odds ratio [OR] 3.42; 95% confidence interval [CI] 1.51-7.75) and seizures (OR 3.89; 95% CI 1.39-10.94) than those with cannabis-only exposure (n = 86). SC-only drug exposure was associated with lower odds of agitation than cannabis-only exposure (OR 0.18; 95% CI 0.10-0.34). In contrast, the group with SC-polydrug exposures (n = 38) had higher odds of agitation (OR 3.11; 95% CI 1.56-7.44) and seizures (OR 4.8; 95% CI 1.80-12.74) than the cannabis-polydrug exposures group (n = 117).

Conclusions: In this multisite cohort of US adolescents assessed in the ED, SC exposure was associated with higher odds of neuropsychiatric morbidity than cannabis exposure providing a distinct neurospychiatric profile of acute SC toxicity in adolescents.

Source: https://pubmed.ncbi.nlm.nih.gov/31285395/?utm_source=no_user_agent&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1z7zlNEMzQex5jriqkhCblNtckSEpT9xYlxxeymU_73UTETESY&fc=20200804213258&ff=20200810015349&v=2.11.5

Heartland

Misguided CBD brands in last minute novel foods panic, ACI warns

Republished by Plato

Published

on

The Food Standards Agency UK (FSA) has given CBD companies a deadline of 31st​ March 2021 to have a validated Novel Food License application … Source:

Continue Reading

Heartland

Does Ontario Farms CBD Really Work?

Republished by Plato

Published

on

Ontario Farms CBD – Whether you're trying to loose weight or develop muscle following a more sensible diet-plan, and training program might you … Source:

Continue Reading

Heartland

CBD Retail Market 2021-28 revolutionary trends with Acreage Holdings, Charlotte's Web Holdings …

Republished by Plato

Published

on

CBD oil businesses can make a good deal of profit once their customer base is established. If you charge an average of $60 per product at a 50% … Source:

Continue Reading
Heartland1 day ago

CBD Vape Oil Market 2021: Global Trends, Business Overview, Challenges, Opportunities …

Heartland4 days ago

Uncategorized5 days ago

What CBD Oil is Right For Me?

Heartland4 days ago

CBD Oil for Beginners

Heartland4 days ago

Heartland4 days ago

Heartland5 days ago

Registration opens for consumable hemp manufacturers and retailers

Heartland3 days ago

Industrial Hemp in Automotive Market Estimated Forecast Analysis 2021-2030

Material2 days ago

Microstructure, characterization of interfacial phases and mechanical properties of high Nb–TiAl/Al2O3 joints brazed by novel Nb particle-reinforced Ag–Cu filler alloy

Heartland5 days ago

CBD Skincare Products Are Popping Up Everywhere — But Do They Actually Work?

Heartland4 days ago

CBP Can't Block Parts Imports, Hemp Machinery Co. Says

Heartland3 days ago

8 of the best cannabis gummies to try right now

Heartland3 days ago

National Hemp Association Awards First Recipients of Social Equity Conscious Business (SECB …

Heartland2 days ago

Drew Carey CBD – How Does It Work For Body Pain

Heartland5 days ago

Heartland4 days ago

Sunnyvale Labs CBD Gummies — Instant Pain Relief Hemp Gummies!

Heartland4 days ago

Heartland4 days ago

Heartland5 days ago

Thc causes me anxiety will cbd be fine? I have the tincture but nervous to try it also how much mg of cbd should i start with for a first dose?

Heartland5 days ago

Material5 days ago

IMC microstructure modification and mechanical reinforcement of Sn–Ag–Cu/Cu microelectronic joints through an advanced surface finish technique

Heartland5 days ago

Hemp Is Creating an EcoRevolution

Heartland5 days ago

CBD to combat physcoactive properties in THC

Heartland4 days ago

Acreage Holdings to Sell Florida Cannabis Operations to Red White & Bloom for $60 Million

Heartland4 days ago

Heartland5 days ago

Former Eaze CEO Pleads Guilty In Bank Fraud Case

Material5 days ago

A new approach of predicting dynamic recrystallization using directly a flow stress model and its application to medium Mn steel

Heartland4 days ago

How CBD Can Help You Live A Healthy Lifestyle, With Medical Marijuana Management Team …

Uncategorized4 days ago

The Daily Hit: The February 25th, 2021

Uncategorized5 days ago

Boston Cannabis Lawyer

Trending

A Cloud Nine Capital Entity Copyright © 2020 – All Rights Reserved Proudly Made in America