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Mechanical properties and bioactivity of porous PLGA/TiO2 nanoparticle-filled composites for tissue engineering scaffolds

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Poly(lactide-co-glycolide) (PLGA) foams and PLGA/titanium dioxide (TiO2) nanoparticle-filled composite foams (porosity > 90%) were produced by thermally induced solid–liquid phase separation (TIPS) and subsequent solvent sublimation. The scaffolds exhibit bimodal and anisotropic pore structures, with tubular macropores (approximately 100 μm in diameter) interconnected by a network of micropores. Quasi-static compression testing and dynamic mechanical analysis were carried out and the results were correlated to the microstructure observed by SEM, confirming the strong anisotropic behaviour of the foams. A study of the collapse mechanism of the foams porous structure revealed that when compressed in the main pore direction, the scaffolds failure mechanism involves an initial “accommodation” of large regions of the porous structure, followed by the collapse of individual pores in different modes. The bioactivity of the scaffolds was demonstrated by immersion in simulated body fluid (SBF) for up to 28 days. Formation of hydroxyapatite crystals on the scaffold surface was confirmed by X-ray diffraction analysis.

This article originally appeared in Composites Science and Technology 67, 2007, Pages 1139-1147.

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Sign up or log in to your free Materials Today account to download the full article.

Poly(lactide-co-glycolide) (PLGA) foams and PLGA/titanium dioxide (TiO2) nanoparticle-filled composite foams (porosity > 90%) were produced by thermally induced solid–liquid phase separation (TIPS) and subsequent solvent sublimation. The scaffolds exhibit bimodal and anisotropic pore structures, with tubular macropores (approximately 100 μm in diameter) interconnected by a network of micropores. Quasi-static compression testing and dynamic mechanical analysis were carried out and the results were correlated to the microstructure observed by SEM, confirming the strong anisotropic behaviour of the foams. A study of the collapse mechanism of the foams porous structure revealed that when compressed in the main pore direction, the scaffolds failure mechanism involves an initial “accommodation” of large regions of the porous structure, followed by the collapse of individual pores in different modes. The bioactivity of the scaffolds was demonstrated by immersion in simulated body fluid (SBF) for up to 28 days. Formation of hydroxyapatite crystals on the scaffold surface was confirmed by X-ray diffraction analysis.

This article originally appeared in Composites Science and Technology 67, 2007, Pages 1139-1147.

Sign up or log in to your free Materials Today account to download the full article.

Source: https://www.materialstoday.com/biomaterials/features/mechanical-properties-and-bioactivity-of-porous/

Metal

Ex-Europe scrap price in Turkey moves up sharply

Two new deep sea scrap deals have been disclosed in the Turkish market.

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Information Provided By:

SteelOrbis Elektronik Pazaryeri A.Ş. (“SteelOrbis”)
19 Mayıs Mahallesi, Atatürk Caddesi
Şeref Yazgan İş Merkezi, No: 72, Kat: 7, D: 18
Kozyatağı – 34736
Istanbul, Turkey

Trade Registration Number : 541892
MERSİS Number : 0470048178400014
Customer Relations Officer : Sinem Alpkaya
Tel : +90 216 468 10 50
Fax : +90 216 386 41 08

This Information Form has been drawn up in order to provide information to the customer (“Customer”) who seeks a free trial on an electronic environment for the purpose of benefiting from the services offered by the SteelOrbis website at “www.steelorbis.com” prior to acceptance of the Membership Contract, and it allows the Customer to gain clear information on the terms and conditions of the membership to be established as well as to review the text of the Contract in question.

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– The Customer selects the “Free Trial” option on the home page at https://www.steelorbis.com.
– The Customer provides all information requested in the “Free Trial Application” form displayed on the screen and confirms it.
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You can either save the Membership Contract on your computer or make print-outs of it for storage. The Membership Contract accepted and confirmed by the Customer is not kept by SteelOrbis. You can always get access to the standard Membership Contract displayed on the website. However, as amendments may be made to the standard Contract, it may include some variations in comparison with the text approved by you. Accordingly, it may not be possible for you to access on the website the text you originally approved.

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Source: https://www.steelorbis.com/steel-prices/steel-prices-market-analyses/scrap-and-raw-materials/ex_europe-scrap-price-in-turkey-moves-up-sharply-1187817.htm

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Metal

Indian government sets up special fund for completion of stalled affordable housing …

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The Indian government has set up a $3.5 billion special fund to facilitate completion of stalled affordable housing projects across the country, a government official said on Thursday, February 25.

The sources said that fund will be utilized to complete an estimated 16 affordable housing projects involving 4,000 homes and deliver them to customers during the fiscal year 2020-21.

The government has estimated that housing projects worth $63 billion have been stalled across the country, with builders unable to service their debt liabilities and banks forced to write off loans.

Source: https://www.steelorbis.com/steel-news/latest-news/indian-government-sets-up-special-fund-for-completion-of-stalled-affordable-housing-projects-1187813.htm

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Metal

Indian government sets up special fund for completion of stalled affordable housing …

Republished by Plato

Published

on

The Indian government has set up a $3.5 billion special fund to facilitate completion of stalled affordable housing projects across the country, a government official said on Thursday, February 25.

The sources said that fund will be utilized to complete an estimated 16 affordable housing projects involving 4,000 homes and deliver them to customers during the fiscal year 2020-21.

The government has estimated that housing projects worth $63 billion have been stalled across the country, with builders unable to service their debt liabilities and banks forced to write off loans.

Source: https://www.steelorbis.com/steel-news/latest-news/indian-government-sets-up-special-fund-for-completion-of-stalled-affordable-housing-projects-1187813.htm

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