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Marijuana impairs growth in mid-gestation fetuses

Published

16 years ago

March 1, 2005

Marijuana (Cannabis sativa) is the most commonly used illicit drug by pregnant women, but information is limited about the effects of prenatal cannabis exposure on fetal development. The present study evaluated the influence of early maternal marijuana use on fetal growth. Women electing voluntary saline-induced abortions were recruited at a mid-gestational stage of pregnancy (weeks 17-22), and detailed drug use and medical histories were obtained. Toxicological assays (maternal urine and fetal meconium) were used in conjunction with the maternal report to assign groups. Subjects with documented cocaine and opiate use were excluded. Main developmental outcome variables were fetal weight, foot length, body length, and head circumference; ponderal index was also examined. Analyses were adjusted for maternal alcohol and cigarette use. Marijuana (n=44)- and nonmarijuana (n=95)-exposed fetuses had similar rates of growth with increased age. However, there was a 0.08-cm (95% CI -0.15 to -0.01) and 14.53-g (95% CI -28.21 to 0.86) significant reduction of foot length and body weight, respectively, for marijuana-exposed fetuses. Moreover, fetal foot length development was negatively correlated with the amount and frequency of marijuana use reported by the mothers. These findings provide evidence of a negative impact of prenatal marijuana exposure on the mid-gestational fetal growth even when adjusting for maternal use of other substances well known to impair fetal development.

Source: https://pubmed.ncbi.nlm.nih.gov/15734273/?utm_source=no_user_agent&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1z7zlNEMzQex5jriqkhCblNtckSEpT9xYlxxeymU_73UTETESY&fc=20200804213258&ff=20200812123047&v=2.11.5

Related Topics:cannabis development growth heartland marijuana medical

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Northeast Kingdom Hemp – Organic CBD Products

Northeast Kingdom Hemp prides itself in practicing sustainable organic farming that produces the healthiest and most precise small-batch CBD possible. All of our products are grown directly on our farm. Using state of the art in-house extraction methods we then produce the cleanest, highest quality, oils.

Our in-house small batch C02 Extraction techniques capture the full power of hemp in every bottle. Our attention to quality yields CBD oils that are pure, great tasting, and teeming with naturally occurring phytocannabinoids, terpenes, and flavonoids that are largely lost with more large scale industrial extraction methods.

ALL OF OUR CBD OILS ARE 100% USDA CERTIFIED ORGANIC

Because we perform the entire process from planting to bottling right here on the farm, we know that every step is done right to give you the purest healthiest CBD oils available.

Published

1 hour ago

January 20, 2021

Republished by Plato

ALL OF OUR CBD OILS ARE 100% USDA CERTIFIED ORGANIC

Because we perform the entire process from planting to bottling right here on the farm, we know that every step is done right to give you the purest healthiest CBD oils available.

Source: https://nekhemp.com/blog/

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Why Our CBD Gummies Are So Popular

Our CBD gummies are on another level! We’ve heard about how other CBD Gummies don’t taste very good. However, we’ve managed to find the perfect balance between the right amount of CBD and taste. If you have a sweet tooth you’ll love these CBD Gummies among other reasons.

Published

2 hours ago

January 20, 2021

Republished by Plato

What Do CBD Gummies Taste Like?

A common question we get is what do our CBD Gummies taste like? The taste is a fruity mix with notes of sour candy. They come in worm shapes and each one has 50 mg of CBD. However, unlike other CBD Gummies we don’t compromise on the taste. We realized that not many people enjoy the Earthy-bitter flavor of CBD. Therefore, they are sweet and even without the CBD they taste amazing!

Side Note: These Gummies are not diabetic or vegan friendly. The reason we didn’t decide to go that route is because of the taste. CBD alone already provides a different flavor. Therefore, we wanted a product that people are already familiar with. This product is great for CBD newcomers.

How CBD Gummies Are Different

Let’s face it, you probably don’t have much time for anything let alone taking in certain forms of CBD. You have to get the CBD that agrees with your lifestyle and for the person on the go our CBD Gummies are perfect. You simply open the package, throw a piece in your mouth and move on with your day. No questions, no preparations, and no need to carry any device around. You will also be free from any pressures on the duration it takes to consume CBD.

Some people who have issues with smoking or vaping their CBD find that CBD Edibles are equally as good. However, the main difference between ingesting your CBD VS. Vaping/Smoking is the absorption rate. Whenever you vape or smoke anything that product tends to enter into your system within minutes. Anything you eat or ingest can take between an hour to an hour and a half before you feel that product working.

CBD Gummies Will Not Get You High

Just like all of our CBD products – our Gummies are not meant to get you high. Yes, it takes longer for the CBD to hit your system this way; however, they are still non-psychoactive. All of our CBD products have below 0.03% THC so you’re not getting enough to produce a high. Also, our Gummies come from legally grown Hemp – not from Marijuana.

Another thing to consider is that even if you take the whole bag – it still won’t get you high. You might feel drowsy, upset stomach, or other unpleasant side effects. An important thing to note is that according to the World Health Organization (WHO) the toxic dose of CBD is 20,000 mg. A comfortable dosage that we recommend is 1 Gummy Worm, but dosages can vary depending on tolerance.

Drug Test

Although our CBD has about 0.03% of THC or less we get asked if you’ll pass a drug test. In short, you should be able to pass a drug test taking CBD Gummies but it can vary depending on the brand. Our lab test results for our CBD Gummies shows that our CBD has Non-Detectable traces of THC. However, if you’re buying a different brand of Edibles you’ll want to be sure you’re getting low to undetectable traces of CBD.

If you’re worried about passing a drug test we recommend not taking CBD for a while. This is of course assuming you know when you’re going to be drug tested. Also, CBD Isolate typically has less traces of THC than Full Spectrum CBD. This is because CBD Isolate separates the CBD from all of the other cannabinoids. This produces a more pure form of CBD which our Gummies use.

Conclusion

Why Our CBD Gummies Are So Popular

Our Gummies are among the most popular products that we carry. Aside from the convenience and strength factors; we believe the taste of these Gummies is one of the biggest reasons for their popularity. Although, they can’t get you high, we’re sure you’ll love the experience. If you are new to CBD this is the best beginners product because it gives you the right amount of CBD.

Source: https://savagecbd.com/blogs/savage-cbd/why-our-cbd-gummies-are-so-popular

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Purification and Biochemical Characterization of Sucrose synthase from the Stem of Nettle (Urtica dioica L.)

Sucrose synthase is a key enzyme in sucrose metabolism as it saves an important part of sucrose energy in the uridine-5′-diphosphate glucose (UDP-glucose) molecule. As such it is also involved in the synthesis of fundamental molecules such as callose and cellulose, the latter being present in all cell walls of plant cells and therefore also in the gelatinous cell walls of sclerenchyma cells such as bast fibers. Given the importance of these cells in plants of economic interest such as hemp, flax…

Published

2 hours ago

January 20, 2021

Republished by Plato

. 2021 Jan 16;22(2):E851.

doi: 10.3390/ijms22020851.

Affiliations

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Lavinia Mareri et al. Int J Mol Sci. 2021.

Abstract

Sucrose synthase is a key enzyme in sucrose metabolism as it saves an important part of sucrose energy in the uridine-5′-diphosphate glucose (UDP-glucose) molecule. As such it is also involved in the synthesis of fundamental molecules such as callose and cellulose, the latter being present in all cell walls of plant cells and therefore also in the gelatinous cell walls of sclerenchyma cells such as bast fibers. Given the importance of these cells in plants of economic interest such as hemp, flax and nettle, in this work we have studied the occurrence of Sucrose synthase in nettle stems by analyzing its distribution between the cytosol, membranes and cell wall. We have therefore developed a purification protocol that can allow the analysis of various characteristics of the enzyme. In nettle, Sucrose synthase is encoded by different genes and each form of the enzyme could be subjected to different post-translational modifications. Therefore, by two-dimensional electrophoresis analysis, we have also traced the phosphorylation profile of Sucrose synthase isoforms in the various cell compartments. This information paves the way for further investigation of Sucrose synthase in plants such as nettle, which is both economically important, but also difficult to study.

Keywords: Sucrose synthase; Urtica dioica; bast fibers; phosphorylation; protein purification.