Connect with us

Heartland

Impact of enzymatic and alkaline hydrolysis on CBD concentration in urine

A sensitive and specific analytical method for cannabidiol (CBD) in urine was needed to define urinary CBD pharmacokinetics after controlled CBD administration, and to confirm compliance with CBD medications including Sativex-a cannabis plant extract containing 1:1 ∆(9)-tetrahydrocannabinol (THC) and CBD. Non-psychoactive CBD has a wide range of therapeutic applications and may also influence psychotropic smoked cannabis effects. Few methods exist for the quantification of CBD excretion in…

Republished by Plato

Published

on

Fig. 2

Hydrolysis efficiency of CBD concentrations in urine after: a authentic non-hydrolyzed and alkaline hydrolyzed pool; b enzyme hydrolysis with 4 h incubation time and three different sources of β-glucuronidase (E. coli, Red Abalone, and H. pomatia) at three different enzyme amounts (2,500, 5,000, and 10,000 units); c enzyme hydrolysis with 16 h incubation time and three different sources of β-glucuronidase (E. coli, Red Abalone, and H. pomatia) at three different enzyme amounts (2,500, 5,000, and 10,000 units). Bars represent mean concentrations (n=3) with standard deviation; * represents significant difference from E. coli β-glucuronidase; + represents significant difference from Red Abalone β-glucuronidase

Source: https://pubmed.ncbi.nlm.nih.gov/23494274/?utm_source=no_user_agent&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1z7zlNEMzQex5jriqkhCblNtckSEpT9xYlxxeymU_73UTETESY&fc=20200804213258&ff=20200811164741&v=2.11.5

Heartland

The symptoms of stress

We all have times when we’re affected by stress; some more often than others….

The post The symptoms of stress appeared first on Nordic Oil Blog.

Republished by Plato

Published

on

We all have times when we’re affected by stress; some more often than others. Stress can have a variety of causes: work, relationships, travel, illness… the list goes on. But sometimes, stress hits seemingly without any real reason. Especially after a year of “the new normal”, we’re all feeling the burden a bit more than usual. And where there is a burden, there is often stress.

But what does stress actually look like? We’ve narrowed down the most common symptoms, and how you can tackle each one.

Bad sleep

One of the first signs that you might be stressed is a decrease in your sleep quality. This can be especially draining, because stress levels increase even more as you get more tired, in a vicious cycle. 

A good night’s sleep is not only crucial for our overall health and wellbeing (as it allows your brain and body to recharge), but can also help you tackle daily stresses more easily, without feeling agitated. 

Once our sleep patterns are regularly disrupted, our minds already start going into overdrive before we fall asleep. Thoughts like “I know for sure that I’ll wake up a couple of times during the night”, or “if I don’t fall asleep fast enough, I won’t get enough sleep” run rampant and keep us awake for even longer.

Welcome offer

Only for new customers, we offer the following coupon code for a 12% discount on your first order.
* valid for all Nordic Oil products (excl. bundles)

drops

Icons/UI/fast-delivery Fast delivery
Icons/UI/plant Made by nature
Icons/UI/security Secure payment

As our lifestyles shift towards healthier habits, prescription drugs for a better sleep don’t seem to fit our needs anymore. Instead, people are turning to natural alternatives that have been proven to help improve sleep, like lavender. CBD is another alternative: by taking CBD a couple of hours before bedtime, you can help your body to balance (a process called homeostasis), which will help you to establish a healthier sleep cycle.

Change of appetite

Another common symptom of stress is a change of appetite and eating habits. People with increased stress levels often report that they feel less hungry, and that even the smell of feed makes them feel nauseous. On the other hand, others report that stress makes them overeat, and often this involves sugary or fatty foods. 

It’s yet to be conclusively proven that CBD can have an influence on our appetite. However, this study has shown that, since CBD can influence serotonin levels, it may curb appetite.
Generally speaking, CBD may not be able to increase or decrease appetite directly, but as a strong regulator, CBD interacts with the hormones that do so.

Hair loss

In extreme cases of consistently elevated stress levels, people can experience hair loss. This is particularly prevalent in younger women.

This report states that, in some cases, the immune system can attack the hair follicles when the stress level is constantly raised. In other cases, “significant stress pushes large numbers of hair follicles into a resting phase”. After a couple of months, this results in hair loss when hair grows out.

Feelings of agitation

When we feel stressed throughout the day, we are more likely to feel agitated and especially worn out in the evening. 

Usually agitation results not only from stress, but also from an imbalance in the body. Whenever our bodies and minds are out of balance, it manifests as stress, and we feel more vulnerable to the slightest inconveniences that happen.

Can CBD help?

As already mentioned, CBD can help to establish healthy sleep routines, as well as help to achieve overall body balance. Of course, as with any lifestyle change, routine is the key to seeing results, so don’t expect to see immediate changes once you start using CBD. Nevertheless, CBD can be a great addition to morning routine for a more relaxed start to the day.

Coinsmart. Beste Bitcoin-Börse in Europa
Source: https://nordicoil.com/blog/the-symptoms-of-stress/

Continue Reading

Heartland

Need to get some cbd seeds for outdoor growing, any recommendations?

Republished by Plato

Published

on

Visit our community site for vetted suppliers at http://theCBD.place. It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.

Coinsmart. Beste Bitcoin-Börse in Europa
Source: https://www.reddit.com/r/CBD/comments/mrvfhj/need_to_get_some_cbd_seeds_for_outdoor_growing/

Continue Reading

Heartland

Love Hemp in UK got the top CBD award if your looking for good CBD

Republished by Plato

Published

on

Visit our community site for vetted suppliers at http://theCBD.place. It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.

Coinsmart. Beste Bitcoin-Börse in Europa
Source: https://www.reddit.com/r/CBD/comments/mrvcwh/love_hemp_in_uk_got_the_top_cbd_award_if_your/

Continue Reading
Uncategorized4 days ago

Halo Collective Announces New Appointment to Board of Directors and Completes Securities Issuance to Independent Consultants, Related Parties, and Suppliers

Metal4 days ago

Registration open for IHEA annual meeting

Heartland2 days ago

Real Brands Inc. CEO Discusses Corporate Goals and Resolve in Audio Interview with …

Heartland4 days ago

Asia Pacific IoT command centre to be established in Adelaide

Heartland2 days ago

Harvard Study Finds Cannabis Effective for Chronic Pain

Heartland1 day ago

First time with WNC or any Indoor CBD in general.

Heartland4 days ago

does cbd help with dizziness?

Heartland1 day ago

Any sales for goin on ?

Heartland2 days ago

I just bought this brand that I have never seen before. Has anyone ever heard of it?

Heartland3 days ago

Are Delta-8 THC Syringes the Most Practical Way to Medicate?

Heartland21 hours ago

At Virtual Forum, Wisconsin Gov. Tony Evers Calls on Lawmakers to Legalize Cannabis

Heartland5 days ago

Heartland5 days ago

Heartland5 days ago

Heartland4 days ago

Heartland4 days ago

Heartland4 days ago

Heartland9 hours ago

The future of the cannabis industry and sports

Heartland5 days ago

Heartland4 days ago

Auckland CBD shop among newest locations of interest for Covid-positive border worker

Heartland4 days ago

Heartland4 days ago

Heartland3 days ago

Heartland2 days ago

Heartland4 days ago

Heartland4 days ago

Heartland4 days ago

Northeast Regulators Talk Cannabis, Real Estate, and Regional Collaboration

Heartland5 days ago

Do you have a favorite CBD product?

News5 days ago

Get Ready for Some Volatility

Heartland4 days ago

Are there usually deals on 4/20? Especially at WNC.

Trending

A Cloud Nine Capital Entity Copyright © 2020 – All Rights Reserved Proudly Made in America