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DMT Can Promote Neurogenesis, Improve Memory, and Spatial Learning, Study Finds

Image via DMT can improve memory and spatial learning by promoting the growth of new neurons in the brain, according

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DMT can improve memory and spatial learning by promoting the growth of new neurons in the brain, according to a new study published in the Translational Psychiatry journal

As the field of research into therapeutic psychedelics grows, a number of studies have reported that ayahuasca, a plant-based brew used for ritual purposes in South America, can effectively treat depression and other mental health issues. N,N-dimethyltryptamine (DMT), the primary psychedelic ingredient in ayahuasca, has intrigued scientists for decades because it is found both in the natural plant world and within the bodies of humans and other animals.

To gain further insight into DMT and its potential therapeutic use, a team of Spanish and Dutch researchers conducted a study on mice to discover exactly how this compound affects the brain. The researchers extracted tissue samples from the brains of 24 healthy mice and treated half of these cultures with DMT. Over the course of a week, researchers observed the growth rate of nerve cells in each sample. 

The study’s authors found that brain cells treated with DMT experienced neurogenesis, or “the process of generating new functional neurons.” In the samples treated with DMT, researchers discovered an increase in growth rates of several different cells that are involved in the creation of new neurons. “In conclusion, this study shows that DMT present in the ayahuasca infusion promotes neurogenesis by stimulating the expansion of neural progenitors populations,” the authors explain. 

Researchers also conducted an additional in vivo experiment to determine whether DMT could actively impact memory or spatial learning. The study reports that mice that had been injected with DMT four days before the experiment were able to escape from a water-filled maze faster than mice that had not received any drug. These results led the authors to conclude that “the neurogenic stimulation observed after DMT treatment correlates with an improvement in spatial learning and memory tasks in vivo.”

Although the study was only conducted on mice, the findings suggest that DMT and ayahuasca could potentially treat neurological and psychological conditions in humans. The neurogenic effects of DMT could possibly help reverse the degradation of nerve cells in Alzheimer’s or other neurodegenerative diseases. Neurogenesis has also been linked to increased neural plasticity, or the ability of the nervous system to adapt to environmental changes, and other studies have found that increased neuroplasticity can help people reduce feelings of depression or anxiety.

“Stimulation of the neurogenic niches of the adult brain can contribute substantially to the antidepressant effects of ayahuasca in recent clinical studies,” the authors concluded. “The versatility and complete neurogenic capacity of the DMT guarantee future research regarding this compound. In addition, its ability to modulate brain plasticity indicates its therapeutic potential for a wide range of psychiatric and neurological disorders, among which are neurodegenerative diseases.”

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Why CBD is a Great Partner for Any Wellness Routine

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Why CBD is a Great Partner for Any Wellness Routine

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In the midst of one of the most life-altering moments of the last fifty years, wellness has vaulted itself into the mindset of almost every individual and household. As the education around mental and physical health continues to expand, conversations around personal wellness have been at the forefront of almost every school, workplace, and community. This has led to the promotion of personal wellness routines that aim to support the physical and emotional aspects of one’s body and mind from day-to-day. Unfortunately, finding ways to positively contribute to one’s own wellness initiatives can be challenging. Fortunately, CBD might be a great tool for helping you do that.

What Even is Cannabidiol?

Cannabidiol, or CBD, is one of over a hundred different chemical compounds (cannabinoids) found in the cannabis plant. When people hear that, they start to make a lot of preconceived judgments based on their previous associations with cannabis as a whole. Or, they limit CBD’s applications to those of a Delta 8 Vape Cartridge. But CBD is only a part of cannabis, and it likely doesn’t contribute to its more political elements. 

Based on a 2018 United Nations health report, researchers found that CBD did not produce or enhance the physiological effects associated with tetrahydrocannabinol, otherwise known as THC. In fact, the study described CBD’s effects in the experiments as being ‘placebo-like’ in nature. This means that the researchers were unable to find an identifiable effect produced by the substance amongst their team of health test subjects. Similarly, this report later went on to detail how CBD ranks very low in terms of abuse potential and very high in terms of tolerance. While further studies are still being conducted, this is extremely promising when it comes to commercial, personal, and medical applications. So, how does CBD positively influence a person’s wellness routines?

What Are the Benefits of CBD? Is it Safe?

What makes cannabidiol so special is its ability to interact with the endocannabinoid system (ECS) found in human beings. This system was discovered in the 1990s and posed a lot of questions about the potential of CBD as it related to human ingestion. The discovery proved that humans produced their own version of cannabinoids, called endocannabinoids, that interact with receptors in the brain. Scientists still aren’t fully clear on all of the functions and nuances of the ECS but do recognize that it plays a significant role in the regulation of a person’s mood, sleep, memory, appetite, and even fertility. These are arguably the five most important pillars that constitute a person’s general wellness.

The unofficial father of cannabinoid research, Dr. Raphael Mechoulam, has explored the uses of CBD and its precursors as tools for not only wellness but medicine. Both CBD and its other compounds have been shown to have antiepileptic properties. Unlike other antiepileptic cannabinoids, such as THC, CBD has been demonstrated to have little to no side effects when ingested. This directly juxtaposes THC, which can produce a ‘high’ as well as a myriad of other psychoactive and physiological effects. This is one of the many reasons why CBD has so much potential as an accessible form of therapeutic treatment. 

If you’re not convinced, just ask the U.S. Food and Drug Administration (FDA). The FDA, back in mid-2018, approved its first drug with an active ingredient derived from a cannabis plant, Epidiolex. Despite the murkiness of current U.S. CBD and cannabis regulations, the FDA couldn’t help but approve the drug due to the strength of its clinical trial results as an effective form of antiepileptic treatment. Obviously, reducing seizures isn’t the mainstay of most people’s wellness routines, but CBD and its precursors have shown to do much more than control epilepsy symptoms.

How Can CBD Contribute to Wellness?

In addition to regulating the symptoms of those with severe epilepsy, CBD also has the potential to treat other – more common – symptoms of various conditions and diseases, namely those of anxiety and depression. These are two of the most common and most crippling mental health afflictions in the world today. It doesn’t help that the symptoms of these mental conditions have been made worse by the pandemic as a whole. That’s one of the main reasons why CBD may make a great partner or supplement for a healthy wellness routine. 

Being able to manage one’s mental health is a crucial part of maintaining one’s personal wellness. That starts with investing in the necessary items, activities, and supplements that will help you live your best life. While CBD has proven to be a consistently safe product, it is always advised that one consult with a medical professional before integrating it into their wellness routine. If anything, medical consultation may help to identify additional ways to support your own mental and physical health.

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Why CBD is a Great Partner for Any Wellness Routine

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Cannabidiol, or CBD, is one of over a hundred different chemical compounds (cannabinoids) found in the cannabis plant. When people hear that, they … Checkout PrimeXBT
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Yo, Sativa, HELP!

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Visit our community site for vetted suppliers at http://theCBD.place. It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.

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Source: https://www.reddit.com/r/CBD/comments/lxdgrv/yo_sativa_help/

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