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Core One Labs Announces Breakthrough in Solving Psilocybin Dosing Problems by Introducing Biosynthetic Psilocybin to its Patented Thinstrip Delivery Method

Core One Labs Inc. (CSE:  COOL), (OTC: CLABF), (Frankfurt: LD62, WKN: A2P8K3) (the “Company”) is pleased to  announce its plans to initiate another intellectual property strategy that will utilize its  patented transmucosal thinstrip delivery method (“thinstrip delivery method”) in  combination with its proprietary biosynthetic psilocybin, developed by its wholly-owned  subsidiary, Vocan Biotechnologies Inc. (“Vocan”). The […]

The post Core One Labs Announces Breakthrough in Solving Psilocybin Dosing Problems by Introducing Biosynthetic Psilocybin to its Patented Thinstrip Delivery Method appeared first on CannabisFN.

Republished by Plato



Ryan Allway

January 12th, 2021


Core One Labs Inc. (CSE:  COOL), (OTC: CLABF), (Frankfurt: LD62, WKN: A2P8K3) (the “Company”) is pleased to  announce its plans to initiate another intellectual property strategy that will utilize its  patented transmucosal thinstrip delivery method (“thinstrip delivery method”) in  combination with its proprietary biosynthetic psilocybin, developed by its wholly-owned  subsidiary, Vocan Biotechnologies Inc. (“Vocan”).

The Company’s existing thinstrip delivery method has been patented for use with THC  and CBD (CannaStripsTM) and has the potential for use with all naturally occurring  compounds, including psilocybin

Through cutting-edge research by the Company’s team at Vocan, a cost effective method  for producing biosynthesized psilocybin has been developed. This low cost method of  psilocybin production, in combination with the incorporation of psilocybin into the  Company’s thinstrip technology, will result in an innovative and first-to-market delivery  method of psilocybin for medical purposes.

Core One’s objective in developing the psilocybin thinstrips is to assist with the delivery  of revolutionary psychedelic treatment methods to address mental health conditions such  as depression, anxiety and addictions.

Methods of accurate dosing and effective delivery of psilocybin have gone relatively  under-researched, and current methods utilized by companies using traditional oral  delivery methods can cause hallucinations, digestive issues, and inaccurate dosages  resulting in undesired side effects. The Company’s patented sublingual transmucosal  (orally dissolvable) thinstrip technology, for the delivery of psilocybin, will aim to address  these issues, and anticipates the provision of many potential advantages and benefits  such as the rapid dissolving and onset of action to the bloodstream, as well as  concentration control and time released dosing. Thinstrip delivery technology is a natural,  non-toxic, biodegradable, biocompatible composite, which is user friendly. The sublingual  polymer thinstrip, with nano particulated active ingredients, skips the digestive system  and is absorbed directly into the bloodstream through the membranes in the mouth, resulting in optimum bioavailability (absorption percentage) of the active ingredients.  Direct delivery to the bloodstream means that dosages can be less potent with the same  affect.

According to the World Health Organization, almost 350 million people worldwide were  affected by depression in 2016. Common antidepressant drugs help maintain the balance  of various hormones and chemicals in the brain which assists in the treatment of  depression.

The Center for Disease Control and Prevention (CDC), reported that the percentage of  people above the age of 12 years using antidepressants in the U.S. rose 12.7% in 2011- 2014. According to MedGadget, the antidepressant drug market was valued at $13.69  billion in 2018 and is expected to reach $15.88 billion by 2025. The CDC said that in the  U.S., antidepressants were the most commonly prescribed drugs in 2013 and from over  16 million long term users, around 70% are female.

“One of the critical issues surrounding the use of psilocybin is accurate dosing in oral  delivery methods. Our breakthrough technology is a game changer in the psychedelic  space and has the potential to revolutionize the way patients receive psychedelics as  medicine and reduce over concentrations and resulting adverse effects.” stated Dr.  Robert E.W. Hancock, Executive Chairman of the Company.

About Core One Labs Inc.  

Core One Labs Inc. is a research and technology company focused in life sciences and  on bringing psychedelic medicines to market through novel delivery systems and  psychedelic assisted psychotherapy. The Company has developed a patent pending thin  film oral strip (the “technology”) which dissolves instantly when placed in the mouth and  delivers organic molecules in precise quantities to the bloodstream, maintaining excellent  bioavailability. With this technology, the Company intends to further develop its  technology to focus on delivering psychedelic molecules with an initial focus on  psilocybin. Core One also holds an interest in walk-in medical clinics which maintain a  database of over 200,000 patients combined. Through research and development in  these clinics, including the integration of its intellectual property related to psychedelic  treatments and novel drug therapies, the Company intends to work towards regulatory  approval for research that advances psychedelic-derived treatments for mental health  disorders.

This article was published by CFN Enterprises Inc. (OTCQB: CNFN), owner and operator of CFN Media, the industry’s leading agency and digital financial media network dedicated to the burgeoning CBD and legal cannabis industries. Call +1 (833) 420-CNFN for more information.

Ryan Allway

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.



UK Government looks to reclassify CBD containing products

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Visit our community site for vetted suppliers at It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.


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William O’Shaughnessy & The Start of Cannabis Medicine

The idea of medicinal marijuana has blossomed out in the last several years, opening up new markets, changing regulatory restrictions and legal mandates, and showing that popular opinion can easily change over time. How it started in the first place is not a story known to all. In fact, most people have no idea that […]

The post William O’Shaughnessy & The Start of Cannabis Medicine appeared first on CBD Testers.

Republished by Plato



The idea of medicinal marijuana has blossomed out in the last several years, opening up new markets, changing regulatory restrictions and legal mandates, and showing that popular opinion can easily change over time. How it started in the first place is not a story known to all. In fact, most people have no idea that it was an Irishman named William O’Shaughnessy who brought cannabis medicine to the Western world.

The world of legal cannabis is ever-changing, with new innovations and products coming out all the time. One of the more exciting additions to the world of marijuana is the inclusion of delta-8 THC. This newest THC compound gives users less psychoactive effects and less anxiety, while still offering a host of medical and recreational benefits. It just so happens we have some great Delta-8 THC deals, for you to go ahead and give it a shot! Judge for yourself if this is a superior form of THC.

Cannabis in history

Before getting into recent history, let’s go back to ancient times. The history of cannabis use as a medicine goes back thousands of years with tons of natural medicine traditions using the plant all over the world for different purposes. In Ayurveda it was used to increase appetite and digestion; to decrease diarrhea, as well as other gastrointestinal issues; as an anti-spasmodic and anti-convulsant; for nervous system issues; skin infections; as an aphrodisiac, or to calm sexual feelings (in later stages of the application); issues with genital and urinary tract function; respiratory issues; infectious diseases; and a host of other problems. If you look at what’s being covered here, it includes ailments of nearly every kind that were being treated by cannabis.

In Traditional Chinese Medicine, cannabis seeds were used as laxatives – although they were simultaneously used to help stop diarrhea, to alleviate thirst, and relieve flux. If it seems weird that cannabis was employed for opposing issues (constipation and diarrhea), this could be explained by a normalization effect on a person’s liver. Repeated vomiting was also treated with cannabis seeds, and regular use of these seeds was said to “render the flesh firm, and prevent old age.”

The Chinese also supposedly used cannabis as an antidiabetic by boiling the seeds in water to make a paste. Cannabis was used for skin ailments, ulcers, wounds, hair loss, and diseases of the lymph nodes which included degenerative, incurable, and intractable illnesses. These are just some examples of how Traditional Chinese Medicine used cannabis. Though many texts have not been made available to the English-speaking world, it is known that cannabis was used in medical applications for at least 1,800 years, and possibly as long as 4,000 years.

Egyption times as well. Called shemshemet, it was used to treat insomnia, nausea, internal hemorrhoids (by way of suppositories), and even eye conditions like glaucoma because of its strong anti-inflammatory properties, which help bring down eye pressures. This anti-inflammatory effect made it good for all kinds of ailments that involve inflammation. Cannabis plant residue has been found on Egyptian artifacts dating back over 4,000 years, and medical marijuana is mentioned in several ancient Egyptian texts including:

  • The Ramesseum III Papyrus (1,700 BC)
  • Eber’s Papyrus (1,600 BC) (This is the oldest known complete text, and thought by many to be a reprint of a text from as long as 1,500 years before this one was made.)
  • The Berlin Papyrus (1,300 BC)
  • The Chester Beatty VI Papyrus (1,300 BC)

By 1,000 years ago, medicinal marijuana use was so widespread in Egypt, that texts found from that time actually encourage citizens to plant their own medicinal cannabis for their own personal use, or to use for trade.

Cannabis history & the Anglo-Saxons

I feel it would be remiss not to mention the history of cannabis in the location that William O’Shaughnessy specifically came from, since this sheds some light on the cannabis culture that existed in his part of the world. It is not one of the more popular or well known cannabis stories, but it is certainly relevant here.

It is thought by many that a nomadic Indo-European tribe – called the Scythians – brought the plant to Eastern Europe around 500 BC. From there it seems likely that Germanic tribes brought it over to Germany, and when the Anglo-Saxons invaded Britain during the 5th century, its thought that the plant at this time entered the British region. Cannabis has a mention in the ‘Anglo-Saxon Herbal’, also known as the ‘Old English Herbal’, which is an illustrated book of botanical medicine attributed to 4th century writers, and which has many similarities to Ayurveda.

This indicates that it was being used for medical treatments, however, what it really became known for in this region, was its fiber. Hemp fiber was used for all sorts of things, particularly by the military. Supplies like rope and sails were made from hemp, for which Russia had been the main supplier. In fact, much like the US grow laws that were enacted in colonial America, and which forced farm owners to grow cannabis for hemp, so too was the case in Britain when in 1533 King Henry VIII also forced landlords to use at least part of their land to grow hemp.

O’Shaughnessy studied chemistry and forensic toxicology at the University of Edinburgh in Scotland, graduating in 1829. At the age of 22, in 1931, while working with cholera patients, O’Shaughnessy helped create the basis for IV replacement therapy. This was done through analyzing the blood of cholera patients and finding a need for more oxygen, as well as finding that they had deficiencies in water, salt, and free alkali, which was improved through infusions of salt.

A couple years later, in 1933, O’Shaughnessy moved to Calcutta, India, as part of the British East India Company, after being rejected for Professor of Medical Jurisprudence at the University of London. And it was here that O’Shaughnessy began his inquest into medical cannabis.

O’Shaughnessy had not set out specifically on the course of cannabis medicine, and in fact, focused on several subjects like chemistry, galvanic electricity, underwater conduction, and botanical pharmacology – which spawned his work on medical marijuana. O’Shaughnessy published his first papers on the use of cannabis medicine and its applications while in Calcutta. In his research he examined folk uses of the plant to validate the information coming from natural medicine traditions, he also found new applications for the plant, and encouraged use of it by his readers for many different purposes including acute rheumatism, as a sleep aid, digestive problems, as a treatment for pain, and a host of other ailments.

Simply writing about these things isn’t what got him recognized, however. He gained popularity instead through real world applications. One of his first big breakthroughs publicly was in being able to quell the rheumatic pain and convulsions of an infant by using cannabis. At approximately 40 days old, the child was unable to eat and was wasting away, as no standard treatment was helping. The parents’ were so distressed that they agreed to the treatment, and cannabis tincture was placed on the baby’s tongue. It eased the convulsions, but greater doses had to be used consequent to tolerance. The infant, however, made a full recovery.

When he later returned to England, he found even greater public success when he was able to quiet the extreme muscle spasms caused by tetanus and rabies, which he did using a cannabis resin. In terms of tetanus, it didn’t rid the sufferer of the disease, but it did greatly reduce symptoms. About tetanus, O’Shaughnessy stated that it was: “next to hydrophobia (rabies), perhaps the most intractable and agonising of the whole catalogue of human maladies.” At that time, having tetanus meant violent convulsions and eventually death, making O’Shaughnessy’s cannabis treatment a godsend to sufferers.

In 1842 he published Bengal Dispensatory and Pharmacopoeia which dedicated 25 pages to the use of cannabis in medicine. This stands as one of the most comprehensive research outputs related to cannabis for that time period.

What about now?

1937 Marihuana Tax Act, and led to the Single Convention on Narcotic Substances treaty, and an essential global ban on both medical and recreational cannabis, as well as hemp production. Over time, the idea of cannabis medicine became non-existent. In fact, not only did it become non-existent in Western medicine and illegal in Eastern medicine, but it became disliked – even hated – with all that accumulated medical evidence being either completely forgotten, or no longer believed.

It took till the 1900’s and researchers like Raphael Mechoulam to re-discover cannabis medicine (which was still suppressed for many decades), and then the eventual easing of laws in different global locations as the expressed danger of cannabis was seen more and more to be unrealistic, while its useful properties were once again brought to light.

Right now in Ireland, O’Shaughnessy’s home country, cannabis is illegal to posses or use with no decriminalization or personal use laws present. Punishments include involuntary community service, fines, and jail time depending on the circumstances of the case. Selling and supply crimes are predictably illegal with prison sentences of up to 10 years for offenders. Cultivation is illegal as well.

Even when it comes to medical cannabis, Ireland only finally updated its laws in 2019, and only to permit a 5-year long research program that allows very limited access to medical cannabis, and only for a very small number of issues. William O’Shaughnessy established some of the very applications of cannabis medicine being researched now, and his own home country still does not pay attention.


It is now getting close to 200 years after William O’Shaughnessy published his Bengal Dispensatory and Pharmacopoeia, and around 4,000 years since the use of cannabis was determined in some locations. Yet now, in 2021, we’re still arguing the legalities and uses of it. Yes, William O’Shaughnessy might have been the father of modern cannabis medicine, but only now is the Western world really taking notice.

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CBD and libido: can CBD improve your sex life?

Thanks to its long list of wellbeing-boosting benefits, CBD is one of the most popular supplements on the market today. But can CBD help you have better sex? It certainly looks that way! In a large survey by Remedy Review, 68% of people said that taking CBD improved their sexual experiences. Scientific research into CBD […]

Republished by Plato



Thanks to its long list of wellbeing-boosting benefits, CBD is one of the most popular supplements on the market today. But can CBD help you have better sex?

It certainly looks that way! In a large survey by Remedy Review, 68% of people said that taking CBD improved their sexual experiences. Scientific research into CBD and sex is still in its early days, but the research we do have seems to agree.

In this article, we’ll explore several ways that CBD can improve your sex life, from getting you in the mood to solving your sexual issues. We’ll also take a look at the science behind these claims, starting with a quick explainer of how CBD works…

How does CBD work?

In the 1990s, scientists discovered that we have a large, complex system called the endocannabinoid system (ECS). It keeps the body in a state of balance, regulating everything from sleep, temperature, pain, appetite, and reproduction. 

The ECS is controlled by a network of chemical messengers called endocannabinoids – that is, cannabinoids that are produced endogenously, or internally. They travel around the body, acting on receptors that tell the ECS to take action.

CBD, or cannabidiol, is one of many chemicals in the hemp plant. It’s extracted from the oil of the plant and used to make CBD consumables, like oils, capsules and creams. CBD is also a cannabinoid, and just like your own endocannabinoids, it can act on ECS receptors in your body.

Researchers have found large concentrations of ECS receptors in the reproductive organs. We’re not sure exactly how CBD interacts with those receptors yet, we just know that it does!

In the meantime, there’s lots of anecdotal evidence – and some scientific support — for the benefits of CBD. In this next section, we’ll explain some of those benefits and what the research says so far.

CBD and libido

Your libido, or your sex drive, is your desire to have sex. Some people just have a naturally higher sex drive than others, but if you find that yours is lower than normal, CBD may be able to help get you back in the saddle, so to speak!

Anecdotally, lots of CBD fans claim that it gets them in the mood. The scientific evidence is a little thin; we know that cannabis activates the part of your brain that controls sexual arousal, but we don’t know if this is specifically because of CBD, or because of other chemicals like THC. Therefore, we can’t say for sure whether you’d get the same benefits from taking CBD alone.

One way CBD definitely can help your libido, though, is by relieving stress and anxiety. Sex can trigger lots of different worries around everything from body hang-ups to performance pressure to traumatic experiences. Your sex drive can also be affected by anxiety conditions like Generalised Anxiety Disorder (GAD), or by worries outside of the bedroom, like work, illness, or money troubles.

Study after study after study shows that CBD can reduce anxiety. The US National Institute on Drug Abuse agrees, stating that CBD reduces the signs of anxiety and stress. This is most likely because it calms the central nervous system, specifically the parts responsible for emotional regulation.

CBD and pleasure

Not only could CBD get you in the mood for sex, it can potentially make it more enjoyable, too. CBD improves blood flow and nerve sensation, with some experts claiming that this makes for more pleasurable sex and better orgasms. The Remedy Review survey seems to back this up, with the majority of those who took CBD for sex reporting that their orgasms were more intense. 

CBD is also proven to boost levels of a neurotransmitter called anandamide. Also called the “bliss molecule”, it works closely with a hormone called oxytocin to make sex feel rewarding and pleasurable. Oxytocin is also responsible for feelings of satisfaction and romantic attachment.

CBD as a lubricant

Some women experience dryness that can make sex uncomfortable or even painful. A lubricant can make sex easier and more enjoyable, and now many brands are adding CBD, too.

Of course, lube works just fine on its own, so why add CBD? The theory is that because it stimulates blood flow and improves sensation, it can also encourage the body to produce more of its own natural lubrication. It’s also a natural anti-inflammatory, which might alleviate any discomfort.

CBD and erectile dysfunction

Erectile dysfunction is the medical term for difficulty either getting or maintaining an erection. The occasional failure to launch is usually nothing to worry about, but if it’s happening all the time and it’s interfering with your sex life, then CBD may be able to help.

The cannabis plant, from which CBD oils and other products are made, has been used in Ayurvedic medicine for thousands of years to improve sexual performance and function. We’re not exactly sure how CBD helps, but we do know that it reduces blood pressure, improves circulation, and promotes blood flow to the genitals – all essential for getting and keeping an erection. 

CBD and pain

For some people, sex is often associated with pain. That can come from sexual problems like vaginismus, where the muscles of the vagina involuntarily contract to prevent penetration, or dyspareunia, where a woman experiences pain during or after sex. It can also be related to painful gynaecological conditions, like endometriosis or polycystic ovarian syndrome (PCOS), or even general health problems. The pain often leads to anxiety around sex, which can make any difficulties even worse.

We already know that CBD relieves anxiety, which can help people feel more physically and mentally relaxed when it comes to sex. Relaxation is especially helpful for conditions like vaginismus and dyspareunia, as it can help resist the urge to tense up. There’s not much research into the topic, but anecdotally, lots of women report that taking CBD oil or capsules, or using CBD topically in a lubricant, helps to ease their symptoms.

If you suffer from any condition that causes you pain, sexual or otherwise, it can have a significant impact on your sex drive and your enjoyment of sex. Thanks to CBD’s anti-inflammatory effects, lots of people report that it helps them to manage chronic pain. And unlike some of CBD’s sexual benefits, we have lots of research on pain to support the anecdotal evidence.

How to use CBD for sex

There are lots of ways to use CBD for sex. To improve libido, relieve anxiety, or promote a feeling of relaxation, go for CBD oils, capsules or edibles, like CBD gummies. For dryness or pain, choose a topical CBD lubricant. And if you want to set the mood or incorporate CBD into the main event itself, try one of the many CBD massage oils on the market.

Remember that it takes a little time for CBD to take effect. Vaping is the quickest as it goes into the bloodstream directly from the lungs. Oils and tinctures are not far behind; they’re absorbed via the blood vessels under your tongue and take around 30 minutes to kick in. Capsules and edibles have to go through your digestive system, and topicals have to be absorbed through your skin, so all of these methods take a little longer.

All that to say: you’ll get best results if you use your CBD of choice at least 30 minutes before you hit the bedroom. Obviously it’s not always possible (or particularly sexy) to plan ahead for sex, and it’s not exactly practical to lube up an hour in advance! So you might want to think about, for example, taking a few drops of CBD oil an hour before and then using a CBD lubricant in the moment. If you do mix products, though, be careful to pay attention to your overall dose.

How much CBD should I take?

Whether you choose capsules, creams or oils, the dosage per serving will be listed clearly on the packaging. If you’ve never used CBD before, around 10-20mg is a good starting dose. Wait at least a few hours to see how it affects you, and if you feel comfortable, then stick with that dose or increase it slightly.

Keep working your way up slowly like this until you achieve the desired effects. If you start to feel any uncomfortable side effects, drop back down to the last comfortable dose and stick with it.

Is CBD safe for sex?

Yes, for most people. We’re not aware of any serious side effects from CBD, although it can interfere with some medications. If you’re taking medication and/or you have an existing health condition, it’s best to check with your doctor first.

Topical CBD products like creams and massage oils often contain other ingredients, like moisturisers or plant extracts. These can cause skin reactions for some people, so if you have sensitive skin or if you suffer from allergies, check the label carefully.

Lubricants are usually designed with intimate skin in mind, but again, check the label to make sure there are no irritants, allergens, or unnecessary ingredients. Generally, the fewer ingredients you’re putting down there, the better!

A word of caution: because CBD is still being studied, experts aren’t entirely sure how it affects fertility. Anecdotally, it seems to be safe, but we just don’t have the scientific evidence yet to say for sure. If you’re trying for a baby, or you’re considering it in the near future, it’s wise to speak to your doctor before using CBD.


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