Heartland
Chemical profiles of cannabis sativa medicinal oil using different extraction and concentration methods
The present study shows the variability in chemical profiles of three different varieties of Cannabis sativa extracts used in medicinal cannabis oil when using two different extraction and evaporation methods. Procedures were compared by analyzing rate of total terpenoids to the principal cannabinoids, tetrahydrocannabinol (THC) and cannabidiol (CBD), using gas chromatography coupled to mass spectrometry (GC-MS). The extraction of inflorescences using soxhlet method showed the highest mass of…
. 2019 Sep 12;1-4.
doi: 10.1080/14786419.2019.1663515. Online ahead of print.
Affiliations
Item in Clipboard
Nat Prod Res. .
Abstract
The present study shows the variability in chemical profiles of three different varieties of Cannabis sativa extracts used in medicinal cannabis oil when using two different extraction and evaporation methods. Procedures were compared by analyzing rate of total terpenoids to the principal cannabinoids, tetrahydrocannabinol (THC) and cannabidiol (CBD), using gas chromatography coupled to mass spectrometry (GC-MS). The extraction of inflorescences using soxhlet method showed the highest mass of final extract. Also, the use of heating and the presence of oxygen when evaporating the solvents, greatly modified the final profiles due to evaporation or chemical reactions. These variations in chemical profiles must be carefully taken into account and standardized in the elaboration of medicinal oils.
Keywords: Medicinal cannabis; extraction methods; mass spectrometry; terpenoids.
Similar articles
-
Therapeutic Use of Δ9-THC and Cannabidiol: Evaluation of a New Extraction Procedure for the Preparation of Cannabis-based Olive Oil.
Curr Pharm Biotechnol. 2017;18(10):828-833. doi: 10.2174/1389201019666171129175655. Curr Pharm Biotechnol. 2017. PMID: 29189144
-
Evaluation of cannabinoids concentration and stability in standardized preparations of cannabis tea and cannabis oil by ultra-high performance liquid chromatography tandem mass spectrometry.
Clin Chem Lab Med. 2017 Aug 28;55(10):1555-1563. doi: 10.1515/cclm-2016-1060. Clin Chem Lab Med. 2017. PMID: 28207408
-
Medicinal cannabis: Principal cannabinoids concentration and their stability evaluated by a high performance liquid chromatography coupled to diode array and quadrupole time of flight mass spectrometry method.
J Pharm Biomed Anal. 2016 Sep 5;128:201-209. doi: 10.1016/j.jpba.2016.05.033. Epub 2016 May 20. J Pharm Biomed Anal. 2016. PMID: 27268223
-
Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer.
Biomed Res Int. 2018 Dec 4;2018:1691428. doi: 10.1155/2018/1691428. eCollection 2018. Biomed Res Int. 2018. PMID: 30627539 Free PMC article. Review.
-
Phytochemistry of Cannabis sativa L.
Prog Chem Org Nat Prod. 2017;103:1-36. doi: 10.1007/978-3-319-45541-9_1. Prog Chem Org Nat Prod. 2017. PMID: 28120229 Review.
LinkOut – more resources
-
Full Text Sources
-
Other Literature Sources
-
Miscellaneous
Florida Bill Aims to Legalize Medical Magic Mushrooms
Affordable cbd oil?
Nanocrystallization of a Ti40 cladding layer by ultrasonic impact to improve burn resistance
Delta 8: Shipping Vape Ban Goes Into Effect Soon – What Does It Means?
Local Turkish DKP grade scrap prices remain stable
Explained: How CBD Oil is Different Than CBD Capsule?
Investigation of severe lunar environmental conditions on the physical and mechanical properties of lunar regolith geopolymers
Wear behavior of nanostructured carbo-austempered cast steels under rolling-sliding conditions
…
…
Dielectric properties and potential applications of alizarin yellow GG-Cu(II) complex film blended with polyvinyl alcohol
Chemical attack and corrosion resistance of concrete prepared with electrolyzed water
Perfect harmony blended with an inked soul, Craig Cavanagh to create sensations in the mind
What can I use besides injection moulding?
A method for estimating superplastic material parameters via free–inflation tests
CBD and Inflammation
Bermuda Prepares To Lock Horns With United Kingdom Over Adult Use Cannabis
Making a Yellow Taxi Toplight
Unnamed Company Tried to Buy Aphria While It Was Negotiating Tilray Merger
Growth kinetics of the FeB/Fe2B boride layer on the surface of 4Cr5MoSiV1 steel: experiments and modelling
Competitive mechanisms occurring during quenching and partitioning of three silicon variants of 0.4 wt.% carbon steels
Correlative cross-sectional characterization of nitrided, carburized and shot-peened steels: synchrotron micro-X-ray diffraction analysis of stress, microstructure and phase gradients
Influence of heavy metal oxides to the mechanical and radiation shielding properties of borate and silica glass system
Activated carbon electrode with promising specific capacitance based on potassium bromide redox additive electrolyte for supercapacitor application
Where To Buy CBD in Fort Worth
Electronic and magnetic properties of graphene quantum dots doped with alkali metals
2:1 or 1:1 CBD to Delta-8 THC Ratio: You Decide!
Fatigue rate evaluation of a transparent polyester resin subjected to low-temperature environments
Is CBD isolate effective for anxiety?
Efficacy of CBD Edibles
-
Heartland1 week agoBiochemical aspects of seeds from Cannabis sativa L. plants grown in a mountain environment
-
Heartland1 week agoHumboldt County, California, permanently bans hemp cultivation
-
Heartland1 week agoCannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective
-
Heartland1 week ago
CBD Oil Recommendations for Autism and ADHD (UK)?
-
News1 week agoFiore Cannabis Announces Sale of Surplus Cannabis Licence to Fund Expansion of Apex Cultivation Facility
-
News1 week agoTILT Holdings Provides Preliminary Fourth Quarter Results, Operational Highlights and 2021 Outlook
-
Uncategorized1 week agoHow to Apply for a Massachusetts Cannabis License
-
Heartland1 week ago
Cannabis Compounds May Help Reduce Lung Inflammation in COVID-19
English
Arabic
Chinese (Simplified)
Dutch
French
German
Italian
Portuguese
Russian
Spanish