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Cannabis for Eating Disorders Like Anorexia

It almost sounds counterintuitive to say it, but yet another possible application of cannabis is in the treatment of eating disorders like anorexia nervosa and bulimia. It’s quite possible that the ability of marijuana to build an appetite, while also helping with symptoms of anxiety, makes it a great treatment option for those suffering from […]

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It almost sounds counterintuitive to say it, but yet another possible application of cannabis is in the treatment of eating disorders like anorexia nervosa and bulimia. It’s quite possible that the ability of marijuana to build an appetite, while also helping with symptoms of anxiety, makes it a great treatment option for those suffering from certain eating disorders.

The new rage in the world of cannabis is the addition of delta-8 THC. Slightly different than delta-9, with less anxiety and psychoactive high, delta-8 is the newest way to get into cannabis. Sound interesting? We can hook you up with the best Delta-8 THC deals so you can investigate for yourself what this new-fangled version of THC is really about!

What is an eating disorder

An eating disorder fits under psychiatric disorders which means first and foremost, there is no medical definition, as in, there is no formal proof that can be made. The definition according to psychiatry, is a disorder “in which the people experience severe disturbances in their eating behaviors and related thoughts and emotions. People with eating disorders typically become pre-occupied with food and their body weight.” This, of course, extends to both ends of the spectrum, those who are overeating for their body weight, and those who are undereating for their bodyweight.

As always with psychological disorders, as there is no medical definition or confirmation, these disorders are identified only through the diagnosis of a doctor, and are therefore subjective in their interpretation. It is also quite possible, because of a lack of a medical definition, that different professionals can levy entirely different diagnoses on the same patient. Having said that, all the examples listed below highlight basic eating disorder categories, each with its own individual symptoms.

According to the National Eating Disorders Association (NEDA), approximately 20 million women and 10 million men will develop an eating disorder at some point in life. The National Institute of Mental Health thinks its even higher, stating that approximately 25% of college students have an eating disorder. It should be remembered that binge eating is included here, and that these statistics come from subjective diagnoses.

Examples?

Six of the more well-known eating disorders are as follows: The most well known is anorexia-nervosa. This eating disorder is characterized by a limitation in food intake, often to the point of extreme malnutrition and physical emaciation. Sufferers often have distorted body images whereby they see themselves as looking different (generally in a negative capacity) then how they actually look, with this discrepancy being focused on weight. Anorexia can affect men or women, but is more commonly seen in women.

2) Bulimia-nervosa is also very well known. It is characterized by a binge/purge pattern in which the sufferer will at times eat large amounts of food (exercising no control in the process), and then work to purge themselves of the food by vomiting, using laxatives, diuretics, enemas, or excessive exercise. While some publications (including the one referenced) name fasting as a method of purging, this would have to be an extreme fast that is intense enough to effect health (it isn’t uncommon to eat a lot at one point, and not get hungry – or choose not to eat – for a much longer than normal period of time.) Much like anorexia, this is more commonly experienced by women.

3) Binge eating is also very common, maybe the most common of all, although to the majority of people it is simply known as ‘overeating’. In binge eating cases, the sufferer will consume excessive calories, experience a lack of control while doing so, but unlike in bulimia cases, will not attempt to expel the excess calories. For this reason, this eating disorder is often associated with being overweight or even obese. In fact, the purging or not purging of the calories is what separates binge eating from bulimia, and in most other ways including the lack of control, large amounts of food and small consumption time, and overall feelings of guilt, embarrassment and shame, the two are about the same. Simply overeating here and there does not constitute entry into this category. Getting an actual diagnosis implies an existing pattern of extreme behavior.

4) The top three disorders are known to most, but here is where it gets a little weird. The next disorder on the list is pica. In pica cases, the individual is likely to be hungry for all kinds of things that aren’t exactly food. This can mean ice, soil, soap, hair, pebbles, detergent etc. As you might imagine with some of the inputs on this list, this can cause some severe issues if the wrong material is ingested, both in a person accidentally poisoning themselves, as well as considering all the infections and injuries that such non-foods can cause internally. Pica can be experienced by anyone, but is generally seen in children, the pregnant, and those with mental disabilities.

5) Next is rumination disorder, which also has a kind of strange definition that those of us in the regular eating world, were probably not aware of. A person with this disorder regurgitates food which has already been swallowed, and then re-chews the food, and swallows once again, or spits it out. This is, essentially, what animals that chew their own cud do, however this is obviously not a characteristic of basic humanity. The reflux occurs within about 30 minutes of a meal, and is completely voluntary, unlike with acid reflux. This disorder can affect men and women, of any age, and often resolves itself when seen in infants. It is a newly recognized disorder.

6) Avoidant/restrictive food intake disorder is generally seen in infants and children only, but can persist into adulthood. It involves a disturbance in eating which can be due to having no interest, or an issue related to the temperature, taste, texture, or smell of something. This is only identified in extreme cases and shouldn’t be confused with simply being picky. People with this disorder might even be diagnosed with other conditions like failure to thrive if they can no longer mature due to lack of nutrients. This disorder has nothing to do with food availability.

How could cannabis help?

research being done which supports the use of cannabis in this way. Less research has been done on anorexia nervosa, which is voluntary, whereas cachexia is not.

However, there are some studies. Cannabis could be useful for helping with the underlying anxiety of some eating disorders, and by supporting a healthy appetite. This study from 2017 which investigated the effects of delta-9 THC on anorexia-nervosa symptoms found no overall increase in BMI, but it did show significant positive results in terms of self-reporting for body care, feelings of ineffectiveness, and general depression. The study authors concluded that delta-9 could be effective in the treatment of psychological symptoms associated with anorexia.

One study even found that using cannabis makes food smell and taste better to the eater, which could be a big draw for those attempting to keep themselves from food.

A systematic review from 2017 investigating the efficacy of cannabis for different psychological and neurodegenerative diseases, included two studies done on cannabis and anorexia. In one study with 11 female participants being given titrated amounts of THC, similar weight gain was shown to diazepam – aka valium. It should be noted that three patients in the THC group had to be withdrawn due to negative side effects, which begs the question of why doses were not individualized based on needs. However, they were not, so it is unclear if the issues experienced could have been alleviated with smaller doses. What is clear is that valium, as a benzodiazepine, is a highly addictive drug, and getting the same benefit from cannabis would mean a significantly safer alternative.

The second study in the review used dronabinol as the form of THC. Dronabinol is a pharmaceutical cannabis medication that does contain THC in it. The placebo-controlled study consisted of two four-week periods with a four-week clean-out period in between. The study presented evidence that dronabinol encouraged weight gain, as much as .73kg compared to the placebo group.

imbalances in the endocannabinoid system, for which cannabis can be useful in regulating. It is speculated that these disorders result from impairments in this system, with the hypothesis that cannabis, as an agent that effects the endocannabinoid system, could be used for positive benefit. As noted by Dr. John Krystal, editor of Biological Psychiatry which put out a report in 2011, “The role of endocannabinoids in appetite control is clearly important. These new data point to important connections between this system and eating disorders.” There is obviously much more to be investigated here.

Issues with cannabis for eating disorders

When it’s said that cannabis can be good for eating disorders, its important to specify which ones. Cannabis has been known to cause episodes of binge eating, so it wouldn’t be the likely answer for someone who is already having issues controlling their overeating. It also might be questionable for those suffering from things like pica – where it could encourage more unnecessary and dangerous eating, or bulimia where it could encourage even bigger binges.

The dose used is also very important to consider when it comes to cannabis for eating disorders. In one study, three participants were removed due to negative side effects with THC, but this was done rather than assessing personal limitations for THC consumption. Accounting for the fact that different people will handle things differently, and require different amounts of medication, is a generally important point in medicine. Not accounting for this is a massive detraction for any study using standardized doses, especially if the study authors did not consider this. However, having said that, it’s important to remember that high doses of THC can cause a cannabis overdose with negative side-effects, and this should always be considered when treating someone who already has mental issues.

Conclusion

New applications for cannabis are being discovered (and rediscovered) every day. Cannabis might not be best for all eating disorders, but it might be useful for those suffering from anorexia-nervosa. These days, everything is about body image and weight. The idea that cannabis might help anorexia sufferers to feel better about themselves, or even add on a few pounds, is incredibly useful, and highlights another great example for medical cannabis.

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Source: https://cbdtesters.co/2021/01/22/cannabis-for-eating-disorders-like-anorexia/

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Charlotte’s Web’s CW Labs Announce New Scientific Collaboration Researching Hemp CBD Efficacy

Harvard Medical School’s Dr. Staci Gruber, Ph.D. is lead investigator BOULDER, Colo., Feb. 24, 2021 /PRNewswire/ – (TSX: CWEB) (OTCQX: CWBHF) Charlotte’s Web Holdings, Inc. (“Charlotte’s Web” or the “Company”), the market leader in hemp CBD wellness products, today announced a long-term scientific collaboration between McLean Hospital, a Harvard Medical School affiliate, and the Company. […]

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Harvard Medical School’s Dr. Staci Gruber, Ph.D. is lead investigator

BOULDER, Colo., Feb. 24, 2021 /PRNewswire/ – (TSX: CWEB) (OTCQX: CWBHF) Charlotte’s Web Holdings, Inc. (“Charlotte’s Web” or the “Company”), the market leader in hemp CBD wellness products, today announced a long-term scientific collaboration between McLean Hospital, a Harvard Medical School affiliate, and the Company. Funding and product support are provided by the CW Labs division of Charlotte’s Web Inc.

Two distinct clinical trials will be overseen by lead researcher/investigator Dr. Staci A. Gruber, Ph. D, Associate Professor of Psychiatry at Harvard Medical School and Director of the MIND program at McLean Hospital in Belmont, Mass. These two studies will investigate the efficacy of a custom-formulated, hemp-derived high-CBD product. Clinical trial results are to be published in 2022. Dr. Gruber is also conducting a number of other studies, including a longitudinal observational study of Veterans who use a Charlotte’s Web product.

Dr. Gruber’s Marijuana Investigations for Neuroscientific Discovery (MIND) Program, established in 2014, is the first of its kind, and is dedicated to studying the long-term impact of cannabis and cannabinoids for medical and adult use which utilizes various clinical and cognitive tools as well as multimodal neuroimaging techniques.

We are honored to be working with Dr. Gruber, Harvard Medical School and McLean Hospital on these important clinical trials. Charlotte’s Web remains dedicated to supporting third-party research on hemp CBD investigated by some of the country’s top scientists.

Tim Orr, President of Charlotte’s Web’s CW Labs divison

For More Information About the MIND Program: https://www.drstacigruber.com/

About the MIND Program:

In 2014 Dr. Staci Gruber launched the Marijuana Investigations for Neuroscientific Discovery (MIND) program at Mclean Hospital, a Harvard Medical School affiliate. The MIND program is the first program of its kind designed to clarify the specific effects of medical cannabis use and is designed to support a wide range of study designs that generate ecologically valid, empirically sound data to close the gap between policy and science. MIND utilizes valid, robust research models and supports numerous projects designed to address the impact of medical cannabis on important variables such as cognition, brain structure and function, mood, conventional medication use, quality of life, pain, sleep, and other health-related measures. Through observational longitudinal investigations, survey studies, and clinical trials of custom-formulated cannabinoid products, MIND aims to examine the unique and synergistic effects of cannabis and its constituents to determine the efficacy of cannabinoids for specific conditions and diseases and to clarify the overall impact of cannabinoid-based treatments on physical and mental health. MIND is poised to improve patients’ overall wellbeing by striving to harness the therapeutic potential while minimizing harms of cannabinoid-based treatment.

About Charlotte’s Web and its CW Labs Division

Charlotte’s Web Labs (“CW Labs”) is the research and development division of Charlotte’s Web, advancing science around hemp-derived phytocannabinoids, terpenes and flavonoid compounds. CW Labs is headquartered at the Hauptmann Woodward Research Institute on the campus of the University at Buffalo’s Jacobs School of Medicine and The Center for Integrated Global Biomedical Sciences, and is part of the State University of New York (SUNY) network of 64 national and international research and medical institutions.

About Charlotte’s Web Holdings, Inc.

Charlotte’s Web Holdings, Inc., a Certified B Corporation headquartered in Boulder, Colorado, is the market leader in the production and distribution of innovative hemp-derived cannabidiol (“CBD”) wellness products under a family of brands which includes Charlotte’s Web™, CBD Medic™, CBD Clinic™, and Harmony Hemp. The Company’s premium quality products start with proprietary hemp genetics that are 100-percent American farm grown and manufactured into whole-plant hemp extracts containing a full spectrum of naturally occurring phytocannabinoids including CBD, CBC, CBG, terpenes, flavonoids and other beneficial hemp compounds. Charlotte’s Web product categories include CBD oil tinctures (liquid products), CBD gummies (sleep, stress, inflammation recovery), CBD capsules,CBD topical creams and lotions, as well as CBD pet products for dogs. Charlotte’s Web is the number one CBD brand in the USA and distributed through more than 22,000 retail locations, select distributors and online through the Company’s website at www.CharlottesWeb.com.

Charlotte’s Web was founded by the Stanley Brothers with a mission to unleash the healing powers of botanicals through compassion and science, benefiting the planet and all who live upon it. Charlotte’s Web is a socially and environmentally conscious company and is committed to using business as a force for good and a catalyst for innovation. The Company weighs sound business decisions with consideration for how its efforts affect employees, customers, the environment, and diverse communities. The rate the Company pays for agricultural products reflects a fair and sustainable rate driving higher quality yield, encouraging regenerative farming practices, and supporting U.S. farming communities. Management believes that its socially oriented and environmentally responsible actions have a positive impact on its customers, suppliers, employees, and stakeholders. Charlotte’s Web donates a portion of its pre-tax earnings to charitable organizations.

Subscribe to Charlotte’s Web investor news.

Original press release

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NCV Newswire
The NCV Newswire by New Cannabis Ventures aims to curate high quality content and information about leading cannabis companies to help our readers filter out the noise and to stay on top of the most important cannabis business news. The NCV Newswire is hand-curated by an editor and not automated in anyway. Have a confidential news tip? Get in touch.


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Source: https://www.newcannabisventures.com/charlottes-webs-cw-labs-announce-new-scientific-collaboration-researching-hemp-cbd-efficacy/

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Is cbd oil worth it’s price or should I stick to flower?

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Tldr- bud or bottle?

Hi

So, I have been smoking high quality outdoor/greenhouse CBD/CBG from Beleafer. Now, my problem is, I dont really feel effects anymore, like, I use my cbd flower to mix with normal high potency weed and it works great, I feel less paranoia, thats all well, but as I say, if I smoke cbd alone its really like im doing something for nothing, this could be because I only get ounces from Beleafer as they last me months, but I probably have a tolerance with each strain by the time I finish it.

My issue is this. I need relief badly(psychological and physical issues), and when I used a high quality cbd oil, it helped, at low 5% dosage, but it was a pretty penny.

When I look at the cbd I want to get now its 129€ for 40% or I can get 2x 20% for the same price. They are 10ml bottles.

HOWEVER, I can get an ounce of indoor cbd for a similar slightly less price, only issue is shipping times, AND – IS SHIPPING OF CBD FLOWER STILL POSSIBLE OR TOTALLY STOPPED? This is probably my only issue now thinking about it.

I digress, basically I can get good strong cbd to smoke for months, or I can get a bottle of oil that could last a month depending if it works and if I stick to dosages instead of just start doing drops all day.

I enjoy cbd and it does work, I just dont know if I have a high tolerance now and it means I have to only fork out on high potency stuff.

Oh, the point of this post is that with smoking cbd, I cant say I feel any health benefits like pain relief etc, however when I used oil I think it definitely helped in more ways than just one (relaxed after a bong)

What would you do in this case? Bud or bottle?

Oh im in France so this makes it difficult with certain brands that dont ship intl.

Source: https://www.reddit.com/r/CBD/comments/lt0hvr/is_cbd_oil_worth_its_price_or_should_i_stick_to/

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