Heartland
Cannabis and Neuropsychiatric Disorders: An Updated Review
Cannabis plant has the scientific name called Cannabis sativa L. Cannabis plant has many species, but there are three main species including Cannabis sativa, Cannabis indica and Cannabis ruderalis. Over 70 compounds isolated from cannabis species are called cannabinoids (CBN). Cannabinoids produce over 100 naturally occurring chemicals. The most abundant chemicals are delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD). THC is psychotropic chemical that makes people feel “high” while CBD is…

Cannabis plant has the scientific name called Cannabis sativa L. Cannabis plant has many species, but there are three main species including Cannabis sativa, Cannabis indica and Cannabis ruderalis. Over 70 compounds isolated from cannabis species are called cannabinoids (CBN). Cannabinoids produce over 100 naturally occurring chemicals. The most abundant chemicals are delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD). THC is psychotropic chemical that makes people feel “high” while CBD is nonpsychotropic chemical. However, cannabinoid chemicals are not found only in the cannabis plant, they are also produced by the mammalian body, called endocannabinoids and in the laboratory, called synthesized cannabinoids. Endocannabinoids are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the mammalian central nervous system including brain and peripheral nervous system. There are at least two types of endocannabinoid receptors (CB1 and CB2) which are G-protein coupled receptors. CB1 receptors are particularly abundant in the frontal cortex, hippocampus, basal ganglia, hypothalamus and cerebellum, spinal cord and peripheral nervous system. They are present in inhibitory GABA-ergic neurons and excitatory glutamatergic neurons. CB2 receptor is most abundantly found on cells of the immune system, hematopoietic cells and glia cells. CB2 is mainly expressed in the periphery under normal healthy condition, but in conditions of disease or injury, this upregulation occurs within the brain, and CB2 is therefore expressed in the brain in unhealthy states. Cannabis and cannabinoid are studied in different medical conditions. The therapeutic potentials of both cannabis and cannabinoid are related to the effects of THC, CBD and other cannabinoid compounds. However, the “high” effect of THC in cannabis and cannabinoid may limit the clinical use, particularly, the study on the therapeutic potential of THC alone is more limited. This review emphasizes the therapeutic potential of CBD and CBD with THC. CBD has shown to have benefit in a variety of neuropsychiatric disorders including autism spectrum disorder, anxiety, psychosis, neuropathic pain, cancer pain, HIV, migraine, multiple sclerosis, Alzheimer disease, Parkinson disease, Huntington disease, hypoxic-ischemic injury and epilepsy. CBD is generally well tolerated. Most common adverse events are diarrhea and somnolence. CBD also shows significantly low abuse potential.
Heartland
Can cbd help prevent hearing loss due to noise?
Visit our community site for vetted suppliers at http://theCBD.place. It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.
Source: https://www.reddit.com/r/CBD/comments/l5b0ik/can_cbd_help_prevent_hearing_loss_due_to_noise/
Heartland
Europe – Where to incorporate CBD affiliate company
I’m looking for advice. I have been working on CBD affiliate sites for the last few months, the sites are starting to have a decent amount of traffic and I need to incorporate a company.
The question is; where should I incorporate it? I’m not looking for massive tax breaks, but rather a country where the banking isn’t a massive headache and a place where I don’t have to be personally present.
Heartland
Plant Power: Everyday Plants That Activate the Endocannabinoid System
When people hear about cannabinoids, they automatically think of cannabis (which makes sense, given the name). What most have yet to realize is that many other plants make cannabinoids too – a lot of everyday flowers, vegetables, and spices that you probably wouldn’t expect. This train of thought was not exclusive to consumers though; until […]
The post Plant Power: Everyday Plants That Activate the Endocannabinoid System appeared first on CBD Testers.

When people hear about cannabinoids, they automatically think of cannabis (which makes sense, given the name). What most have yet to realize is that many other plants make cannabinoids too – a lot of everyday flowers, vegetables, and spices that you probably wouldn’t expect.
This train of thought was not exclusive to consumers though; until recently, even scientists had only been able to identify cannabinoids in the cannabis plant. But current studies have found these compounds in a handful of common, day-to-day plants, including clove, black pepper, cocoa, echinacea, broccoli, ginseng, hops, and even carrots.
But no matter how much of these plants you consume, they won’t feel any type of psychedelic effects. This is because they don’t have the cannabinoids we’re all familiar with, like tetrahydrocannabinol (THC), cannabidiol (CBD), or cannabigerol (CBN). Rather, they have their own compounds that directly engage our Endocannabinoid Systems (ECS).
The ECS is itself only recently discovered, and understanding how different phytocannabinoids interact with this network of neurotransmitters in our bodies can lead to important medical innovations in the future. Ones that are natural, safer for patients, and more focused on plant-based healthcare.
To learn more about cannabis, and for exclusive deals on flowers and other products, subscribe to The CBD Flowers Weekly Newsletter
Pain-relieving drugs made from plants
Chronic pain affects at least 10 percent of the global population, which is approximately 60 million people. However, experts estimate that figure to be closer to 20-25 percent on some countries and regions. Finding a solution that doesn’t put patients at risk for addiction and addition problems, is paramount.
As we humans have done since the dawn of time, we continue looking to the plant world for ways to improve our health and wellbeing. Cannabinoids might be the trendiest at the moment, but they’re certainly not the only plant-based compound that’s been utilized to help fight pain.
Opiates
Opiates get a bad rap because of their high rate for addiction and abuse, but they do have an important place in the world of medicine. Very intense pain, post-surgical or from a broken bone for example, typically won’t respond to cannabinoids. Something stronger like morphine, codeine, and other opiate drugs are sometimes necessary. They have many added ingredients these days, but believe-it-or-not, these medicates have a natural element to them. Opiates are made from opium, which comes from the poppy plant. Just like cannabinoids, these pharmaceutical drugs interact with opiate receptors in the human brain, which is why they can be incredibly effective when used responsibly.
Aspirin
Dating back to ancient Egypt, tea made from the willow tree was used to manage pain and reduce fever. Fast forward a few centuries and scientists are looking at the willow tree yet again, this time isolating the active compound used in that ancient tea – salicylic acid – and used it to formulate numerous medications used to treat pain and inflammation; most notably, aspirin. Salicylic acid is also a very common active ingredient in acne medication.
Anesthetics
Common anesthetics like lidocaine, used routinely by dentists to numb the mouth before initializing treatment, are also distantly related to wild plant – Coca. The leaves of the coca plant were used in the ancient Incan Empire in South America to treat many different levels of pain, from headaches to fractures. Eventually, the coca plant gave way to the drug cocaine, which is an illegal drug of abuse but also a very effective anesthetic.
Plant cannabinoids and the endocannabinoid system
Cannabis has been used medicinally for centuries, but it wasn’t until recently that science started to catch up with what our ancestors have been telling us. Ancient texts from China, Egypt, Tibet, and many other parts of the world hail cannabis as a natural remedy for numerous ailments including pain, inflammation, nausea, anxiety, epilepsy, and even sexual dysfunction. But how can one plant serve so many different functions in the human body? It all boils down to a network of receptors and neurotransmitters known as the Endocannabinoid System (ECS).
Unfortunately, the federally illegal status of cannabis and its use as a recreational drug has been a major hinderance on the ability of researchers to study the full capabilities of this plant. Until recently, most of the information we had came from scientists in Israel, where they had less restrictions when it came to using the plant compounds medicinally.
The Endocannabinoid System (ECS) is involved in multiple physiological processes including appetite regulation, pain threshold, sleep/wake cycles, memory, and mood. It plays a major role in allowing our bodies to achieve homeostasis, or internal balance. The discovery of the ECS shed new light on how and why plant-based cannabinoids, or phytocannabinoids, affect humans in the way they do. In cannabis alone, over 80 phytocannabinoids have been indexed and these compounds exist in many, many plants we consume regularly.
Other plants that engage the ECS
Like cannabis, many other plants have compounds that engage the endocannabinoid system, and with growing attention on this newly-discovered system, the more sources of phytocannabinoids we have the better. While these other plants don’t have cannabinoids as we know them, many of them contains Alkylamides, compounds that are structurally similar to endocannabinoids, and terpenes, that give plants their unique aromas – both of which effectively activate the ECS.
Plants of interest include (but not limited to):
- Black pepper
- Hops
- Helichrysum
- Oregano
- Cinnamon
- Carrots
- Basil
- Cloves
- Lavender
- Rosemary
- Cocoa
- Echinacea
- Black truffles
- Electric daisies
- Liverwort
- Kava
More about plant terpenes
Worth an additional mention since they often work synergistically with cannabinoids, in addition to activating the endocannabinoid system indirectly. Terpenes are a very large and diverse class of organic compounds that are produced by a wide variety of plants, including the ones listed above. In cannabis, they are secreted by the same glands that produce some of the more dominant cannabinoids including THC and CBD. Their role and effects are quite different, however.
Terpenes are aromatic plant oils that, when combined with other plant compounds, create a never-ending palate of scents and flavors. In nature, terps serve as a defense mechanism by deterring herbivores and by attracting predators and parasites that attack herbivores.
Chemically, terpenes are hydrocarbons, and they differ from terpenoids, which typically have added functional groups such as oxygen. The words “terpenes” and “terpenoids” are often used interchangeably but this is incorrect. Terpenes are also the major component of rosin, which a sap/waxy-like substance that is produced when cannabis buds are placed under high heat and pressure. Climate, weather, age and maturation, fertilizers, soil type, and light cycles can have an impact on the development of terpenes.
As far as cannabis goes, terpenes are the key to differentiating the effects and flavor of a strain. Some terpenes are relaxing, like those found in lavender, while others are energizing, like citrus. Some smell fruity, some are piney, others are musky, or even floral. There really is no limit to the variation. So far, over 100 different terpenes have been discovered in cannabis plants alone, and each strain typically has its own unique blend and composition of terps.
Terpenes have long been known to hold great therapeutic value, and some of the more common ones have been studied more extensively, considering they’re found in many different types of legal plants. More research is needed to determine the extent of their medicinal effects when combined with other cannabis plant compounds.
Conclusion
No matter how many veggies you munch on, or how many spices you add to your dish, you won’t get high from it like you would with actual cannabis. Our everyday plants don’t have THC, CBD, or any of the other major cannabinoids, but they have their own structurally similar compounds that engage with our Endocannabinoid Systems and can offer us natural, medicinal possibilities well beyond what science ever believed would be possible.
Thank you for visiting CBDtesters.co, your #1 spot for all cannabis-related news and information. Join us regularly to keep up with the world of legal cannabis, and sign up to our newsletter so you’re always in the know!
RESOURCES:
It Was Just a Matter of Time: GMO Cannabis on Its Way
Compared to Prescription Medication, Medical Cannabis Not Always Affordable Alternative
A Brief History Of CBD The Week in Review: Canadian Cannabis, Antibiotic Resistance, Father’s Day Gift Ideas, and more
Can You Treat COVID-19 With CBD and Reduce Mortality Rates? A New Israeli Research Believes You Can!
Not Just for Getting High – The Underreported Medical Uses of THC
In a world plagued with antibiotic resistance, look to cannabis as a natural alternative
The CBD Flowers Weekly newsletter (your top resource for all things smokable hemp flowers)
The Medical Cannabis Weekly newsletter (International medical cannabis business report)
Cannabis Heroes of History: How Robert Randall Beat the U.S.
The Delta 8 Weekly Newsletter (All you need to know about Delta 8 thc) and the Best Black Friday Delta 8 THC Deals 2020. The best delta-8 THC deals, coupons and discounts.
The Medical Cannabis Weekly Review: Antibiotic Resistance, Cannabis in Italy, CBD for Weight Loss, and more Argentina Allows Cannabis Self-Cultivation
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Source: https://cbdtesters.co/2021/01/26/plants-cannabinoids-endocannabinoid-system/
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