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Applying sewage epidemiology approach to estimate illicit drug consumption in a tropical context: Bias related to sewage temperature and pH

Illicit drug consumption can be estimated from drug target residue (DTR) in wastewater, with the reliability of results being partly linked to DTR stability in the sewage network. However, wastewater temperature and pH drive the stability of molecules and, in this context, tropical conditions must be studied to specify the impact of residence time in the sewage network on DTR degradation. Warmth enhances biotic and abiotic processes such as degradation, leading to a decrease in oxygen content,…

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Illicit drug consumption can be estimated from drug target residue (DTR) in wastewater, with the reliability of results being partly linked to DTR stability in the sewage network. However, wastewater temperature and pH drive the stability of molecules and, in this context, tropical conditions must be studied to specify the impact of residence time in the sewage network on DTR degradation. Warmth enhances biotic and abiotic processes such as degradation, leading to a decrease in oxygen content, and consequently, early diagenesis conditions in wastewater. In this study, we conduct laboratory studies under acidic pH and high temperature (30°C) conditions to determine the degradation half-lives of cocaine (COC), tetrahydrocannabinol, and heroine targets, allowing COC/benzoylecgonine (BZE) ratio variations to be predicted in sewage networks. A rapid COC degradation is observed, as already reported in the literature but without a short-term significant difference between 20°C and 30°C. Acidic pH seems to prevent degradation. Thus, theoretically, the use of COC as DTR is only reliable in acidic conditions, with the decrease in COC concentration being 6% at 8h, but over 40% in other conditions. By contrast, the use of BZE as DTR to estimate COC consumption, which is performed in practice, can be undertaken with the same back-calculation equation as used in temperate countries. However, 11-nor-delta-9-carboxytetrahydrocannabinol stability is more influenced by high temperature: concentration levels after 24h are 20% lower at 30°C than at 20°C, corresponding to a 20% and 40% decrease, respectively. Based on a mean residence time of 8h, underestimated cannabis consumption is close to 15% in tropical contexts, which is double that of temperate areas.

Keywords: Cannabis; Degradation; H(2)S; Half-life; Illicit drugs; Wastewater.

Source: https://pubmed.ncbi.nlm.nih.gov/28193575/?utm_source=no_user_agent&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1854v2hhZntXmjLwJ2c8ICqk5dHszkjKaegUwgxvTg53irEIHf&fc=20200804212743&ff=20200812123339&v=2.11.5

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Need to get some cbd seeds for outdoor growing, any recommendations?

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Visit our community site for vetted suppliers at http://theCBD.place. It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.

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Source: https://www.reddit.com/r/CBD/comments/mrvfhj/need_to_get_some_cbd_seeds_for_outdoor_growing/

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Love Hemp in UK got the top CBD award if your looking for good CBD

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Visit our community site for vetted suppliers at http://theCBD.place. It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.

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Source: https://www.reddit.com/r/CBD/comments/mrvcwh/love_hemp_in_uk_got_the_top_cbd_award_if_your/

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Will CBD help appetite?

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Visit our community site for vetted suppliers at http://theCBD.place. It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.

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Source: https://www.reddit.com/r/CBD/comments/mrv114/will_cbd_help_appetite/

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