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A preliminary investigation of lung availability of cannabinoids by smoking marijuana or dabbing BHO and decarboxylation rate of THC- and CBD-acids

Highly potent cannabis concentrates obtained by butane or by supercritical carbon dioxide-extraction are gaining popularity. These extracts called butane hash oil (BHO) with Δ⁹-tetrahydrocannabinolic acid A (THCA) contents above 60% are consumed by flash vaporization on a glowing titanium nail, followed by inhalation of the resulting vapor through a water pipe in a single puff – a technique referred to as “dabbing”. We herein investigated the decarboxylation rate of THCA during artificial…

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Highly potent cannabis concentrates obtained by butane or by supercritical carbon dioxide-extraction are gaining popularity. These extracts called butane hash oil (BHO) with Δ9-tetrahydrocannabinolic acid A (THCA) contents above 60% are consumed by flash vaporization on a glowing titanium nail, followed by inhalation of the resulting vapor through a water pipe in a single puff – a technique referred to as “dabbing”. We herein investigated the decarboxylation rate of THCA during artificial smoking of cannabis plant material and simulated dabbing, and the lung availability of Δ9-tetrahydrocannabinol (THC) which we define as the recovery of THC in the smoke and vapor condensates. Preliminary smoking and dabbing experiments were performed using an apparatus built in-house. Due to availability of cannabidiol (CBD)-rich hemp in Switzerland, we included a sample of CBD flowers in our experiments and investigated the decarboxylation and recovery of cannabidiolic acid (CBDA) and CBD, respectively. Decarboxylation of THCA and CBDA during combustion of the plant material and vaporization of the BHO, respectively, was complete. The high recovery of total THC (75.5%) by dabbing cannot be achieved by smoking marijuana. Lung availability ranged from 12% for mixed cannabis material with a rather low THC content, to approximately 19-27% for marijuana flowers, similar for THC in marijuana as for CBD in CBD-rich marijuana. In reality, when smoking a joint, further losses in recovery must be assumed by additional sidestream smoke. The rather high lung availability of THC via dabbing can explain the increased psychoactive and adverse effects associated with this new trend of cannabis consumption.

Keywords: BHO; Cannabis concentrate; Dabbing; Lung availability; Marijuana.

Source: https://pubmed.ncbi.nlm.nih.gov/30638755/?utm_source=no_user_agent&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1TUbR4JfRTv1rbahLd1HaiF0w5ryO5ocWB3_xk3Prq78L0AEhI&fc=20200804222312&ff=20200815171241&v=2.11.5

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What kind of pod systems can you use with cbd?

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Hey, I’ve recently started using cbd gummy’s to help with my anxiety attacks, but I’ve noticed it doesn’t take effect fast enough to really help. I want to try out vaping it but I am not really interested in using disposables. Can you use any kind of pod systems to vape eliquid?

Source: https://www.reddit.com/r/CBD/comments/l49kgi/what_kind_of_pod_systems_can_you_use_with_cbd/

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pre-made tincture are more expensive?

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I’ve been looking around for tinctures, mainly full spectrum 1000mg/30 mL. The price for this has been hovering around $60-$70 from several vendors. However as I was browsing through powders, I found 1000mg full spectrum powder for just $30 at cbdistillery, at half the cost of pre-made full spectrum tincture. Is the price difference mainly just convenience? Pre-made tinctures seem to be far more expensive than a DIY. I understand you’d need to buy a carrier oil to make a tincture, so the total cost at first purchase would be more than $30, but one would be set for making additional cbd tinctures in the future.

Source: https://www.reddit.com/r/CBD/comments/l49ga2/premade_tincture_are_more_expensive/

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Have you guys noticed any synergetic effect of drinking coffe after/before taking cbd?

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Visit our community site for vetted suppliers at http://theCBD.place. It’s time that this subject was given more internet exposure. We are here to discuss topics related to medical marijuana and our experiences using CBD. Please do not assume that anyone here is a medical professional.

Source: https://www.reddit.com/r/CBD/comments/l4749q/have_you_guys_noticed_any_synergetic_effect_of/

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